Protein Alignment gsb-n and PAX4

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 112/276 - (40%)
• Similarity: 153/276 - (55%)
• Gaps: 28/276 - (10%)

  Fly    20 GQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIRP 84
            |...:|||||:|:||||||...|.:||.:|.||:|||.|||.|:||:|||||||.||..||.:.|
Human     5 GISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEP 69

  Fly    85 GVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFA---DPPSTSSISRLLRG--SD 144
            ..||||||::.:|.:..||.:|:.|.|::|:|||:.:|..||..   ..||.|||:|:||.  .|
Human    70 KGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQED 134

  Fly   145 RGSEDGR---KDYTINGILGGRDSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQY 206
            :|....|   .......:|.......:...:.||     ...|:||.|:..|.||||:.|.|.||
Human   135 QGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPG-----TGHRNRTIFSPSQAEALEKEFQRGQY 194

  Fly   207 PDVYTREELAQTTALTEARIQVWFSNRRARLRKHS--------GGSNSGLSP-------MNSGSS 256
            ||...|.:||..|:|.|..::||||||||:.|:..        .|::.||:.       :::..|
Human   195 PDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQS 259

  Fly   257 NVGVGVGLSGATAPLG 272
            ...|......|..|||
Human   260 PGSVPTAALPALEPLG 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	65/123 (53%)
		Homeodomain	183..239	CDD:459649	29/55 (53%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	65/123 (53%)
		Homeodomain	172..227	CDD:459649	29/54 (54%)