DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gsb-n and gsb

DIOPT Version :9

Sequence 1:	NP_523862.1	Gene:	gsb-n / 38004	FlyBaseID:	FBgn0001147	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_523863.1	Gene:	gsb / 38005	FlyBaseID:	FBgn0001148	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	227/472 - (48%)
Similarity:	274/472 - (58%)	Gaps:	107/472 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SANSLRPLFAGYPFQGQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCV 69
            ||.::.|.|.||||||||||||||||||||||||||||.:||||||:||||||||||||||||||
  Fly     4 SALNMTPYFGGYPFQGQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCV 68

  Fly    70 SKILNRYQETGSIRPGVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PP 131
            ||||||:||||||||||||||||:|.:|:||:||:||::..|.|||||||.|||:.|..|   .|
  Fly    69 SKILNRFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAP 133

  Fly   132 STSSISRLLRGSDRGSEDGRKDYTINGILGG-----RDSDISDTESEPGIPLKRKQRRSRTTFTA 191
            |.||||||||||. ||   ...::|:|||||     ...|.|:.::||.:.||||||||||||:.
  Fly   134 SVSSISRLLRGSS-GS---GTSHSIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSN 194

  Fly   192 EQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSG----------GSNS 246
            :|::||||.|:|||||||||||||||:|.|||||:|||||||||||||...          .::.
  Fly   195 DQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFAPTSTSF 259

  Fly   247 GLSPMNSGSSNVGVGVGL--------SGA-TAPLGYGPLGVGSMAGYSPAPGTTATGAGMNDGVH 302
            |.:|..|.:....:|:.|        ||| .....||    ||:|..|||..|:.|.:
  Fly   260 GATPTTSAAPAPNMGMSLYSSQSWPSSGAYENHAAYG----GSVASMSPASSTSGTSS------- 313

  Fly   303 HAAHAPSSHHSAATAAAAAHHHTQMGGYDLVQSAAQHGFPGGFAQPG----------HFGSQN-- 355
             |||:|                        ||:.||        |||          ..||.|
  Fly   314 -AAHSP------------------------VQTQAQ--------QPGTGSEFMTSTYGVGSSNAT 345

  Fly   356 YYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAAANYNAHVAQHQLN 420
            |....||      ..:..|.|..::. |...|...|....||.|.  :|:.|.::
  Fly   346 YPSAAYS------MPQTPATSAEQLR-SQFASAAASGSHHPSTWD--SYNFAGSF---------- 391

  Fly   421 DYAAAAAHGNPASAYSH 437
             :..|:|.||..|.|.|
  Fly   392 -FPPASAAGNHISGYHH 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	PAX	20..141	CDD:278709	98/123 (80%)
gsb-n	NP_523862.1	Homeobox	185..238	CDD:278475	42/52 (81%)
gsb	NP_523863.1	PAX	19..143	CDD:128645	98/123 (80%)
gsb	NP_523863.1	homeodomain	186..243	CDD:238039	46/56 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469590
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	1	0.900	-	-		E1_KOG0849
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	385	1.000	Inparanoid score	I4121
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1126858at2759
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		mtm6578
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1205
	10	9.900