DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gsb-n and Poxn

DIOPT Version :9

Sequence 1:	NP_523862.1	Gene:	gsb-n / 38004	FlyBaseID:	FBgn0001147	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001261016.1	Gene:	Poxn / 36741	FlyBaseID:	FBgn0003130	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	136/459 - (29%)
Similarity:	182/459 - (39%)	Gaps:	145/459 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PFQGQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGS 81
            |..||..||||||||:||||||:.:|.:||::|..|||||.|||||.||||||||||.|:.||||
  Fly     2 PHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGS 66

  Fly    82 IRPGVIGGSKPK-VTSPEIETRIDELRKENPSIFSWEIREKLIKEGFADP---PSTSSISRLLRG 142
            ||||.|||||.| |.:|.:..:|..|::||..:|:|||||:|.::...||   ||.|||:|:||.
  Fly    67 IRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRN 131

  Fly   143 SDRGSEDGRKDYTINGILGGRDSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYP 207
            |...:::                                       .|:.|..|...|.:
  Fly   132 SGLWTDE---------------------------------------MTSSQQNAAAAAAA----- 152

  Fly   208 DVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGSNSGLSPMNSGSSNVGVGVGLSGATAPLG 272
                                       |....|..|         ||.||   |.|......|:.
  Fly   153 ---------------------------AAAAAHQAG---------SGPSN---GYGGQAPPPPVT 178

  Fly   273 YG---PLGVGSMAGYSPAPGTTATGAG-------------MNDGVHHAAHAPSSHHSAATAAAAA 321
            ..   |....|:|.|:..|......||             |..|..|..:...|....:.:|...
  Fly   179 VAPPTPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDLSYSALHK 243

  Fly   322 H--------HHTQMGGYDLVQSAAQHG----FPGGF---AQPGHFGSQNYYHQDYSKLTIDDFSK 371
            |        ::||  .:...|:||..|    :.||:   |......|        |...:..|:|
  Fly   244 HWLWNPSLLYYTQ--AHIQAQAAASGGQFLPYAGGYLPHAMAAAAAS--------STSALGGFTK 298

  Fly   372 LTADSVSKISPSL---HLSDNYSKLEAPSNWSQAAYHAAANYNAHVAQHQLNDYAAAAAHGNPAS 433
             :..|:...:|..   .|||..|...:|:..|..   |:...|.          |.:|...:|.|
  Fly   299 -SESSIDLSTPGAAGDALSDCDSGKSSPAALSLT---ASGGGNG----------AGSAPEASPGS 349

  Fly   434 AYSH 437
            ..||
  Fly   350 TLSH 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	PAX	20..141	CDD:278709	76/124 (61%)
gsb-n	NP_523862.1	Homeobox	185..238	CDD:278475	5/52 (10%)
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	78/127 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840