Protein Alignment gsb-n and EVX2

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001073927.1
• Gene: EVX2 / 344191
• HGNCID: 3507
• Length: 476
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 92/400 - (23%)
• Similarity: 133/400 - (33%)
• Gaps: 132/400 - (33%)

  Fly    37 LPNHIRLKIVEMAASGVRPCVISRQLRVS--HGCVSKI----------LNRYQETGS-------- 81
            |.|.....::|...:...|..:|.:|..:  |..:.::          |...|.|||
Human    28 LSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGSESTVSSEI 92

  Fly    82 -------IRPGVIGGSKPKV-TSPEIETRIDELR----------KENPSIFSWEIREKLIKEGFA 128
                   .:||....:..:. .|.::|.....||          |||..            :|:|
Human    93 SSAAESRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAQLKENNG------------KGYA 145

  Fly   129 DPPSTSSISRLLRGSDRGSEDGRKDYTINGILGGRDSDISDTESEPGIPLKRKQRRSRTTFTAEQ 193
            :..|.:..:....||..||        ::|..||.....:...|..|..   :.||.||.||.||
Human   146 ESGSAAGTTTSASGSGLGS--------LHGGSGGSGGSAALGGSGSGAD---QVRRYRTAFTREQ 199

  Fly   194 LEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRAR---------------------L 237
            :..||:.|.|..|.....|.|||....|.|..|:|||.|||.:                     :
Human   200 IARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYM 264

  Fly   238 RKHSGGSNSGLSPMNSGSSNVGVGVGLSGATAPLGYGP-LGVGSMAGYSPAPGTTATGAG----- 296
            ..|:..:.|...|.:|              ..||.|.| :||.:.|..:.|.|..|..:.
Human   265 MTHAAATGSLPYPFHS--------------HVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATS 315

  Fly   297 -----------------------MNDGVHHAAHAPSSHHSAATAAAAAHHHTQMGGYDLVQSAAQ 338
                                   .:.|::.|..|.:..:|||:|||||     ........|||.
Human   316 IRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAA-----AAAAAAASSAAA 375

  Fly   339 HGFP--GGFA 346
            .|.|  ||.|
Human   376 AGAPPSGGSA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	24/141 (17%)
		Homeodomain	183..239	CDD:459649	26/76 (34%)
EVX2	NP_001073927.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..185		11/50 (22%)
		Homeodomain	189..245	CDD:459649	26/55 (47%)