Protein Alignment gsb-n and Shox2

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_037160.2
• Gene: Shox2 / 25546
• RGDID: 3674
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 94/328 - (28%)
• Similarity: 116/328 - (35%)
• Gaps: 114/328 - (34%)

  Fly   142 GSDRGSEDGRKDYTINGILGGR------DSDISDTESEPGIP----------------------- 177
            |:..|...|       |..|||      |...::...|||.|
  Rat    77 GAGGGGAGG-------GAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAKGMEDEG 134

  Fly   178 -LKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHS 241
             .|.|||||||.||.|||..|||.|..|.|||.:.||||:|...|:|||:||||.||||:.||
  Rat   135 QTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK-- 197

  Fly   242 GGSNSGLSPMNSGSSNVGVGVGLSGATAPLGYGP-LGVGSMAGYSPAPGTTATGAGMNDGVHHAA 305
                      .....:.||.:|.:.........| :.||::.  .|....:           |..
  Rat   198 ----------QENQLHKGVLIGAASQFEACRVAPYVNVGALR--MPFQQDS-----------HCN 239

  Fly   306 HAPSSHHSAA-----TAAAAAHHHTQMGGYDLVQSAAQHG----FPGGFAQPGHFGSQNYYHQDY 361
            ..|.|....|     :|.|.||||       |....|.|.    ||   |.|  ||.
  Rat   240 VTPLSFQVQAQLQLDSAVAHAHHH-------LHPHLAAHAPYMMFP---APP--FGL-------- 284

  Fly   362 SKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAAANYNAHVAQHQLNDYAAAA 426
                  ..:.|.|||.|                |.|..:.||.....:.|:.:|..:|.....||
  Rat   285 ------PLATLAADSAS----------------AASVVAAAAAAKTTSKNSSIADLRLKAKKHAA 327

  Fly   427 AHG 429
            |.|
  Rat   328 ALG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199
		Homeodomain	183..239	CDD:459649	35/55 (64%)
Shox2	NP_037160.2	Homeodomain	141..197	CDD:459649	35/55 (64%)
		OAR	311..327	CDD:461067	3/15 (20%)