Protein Alignment gsb-n and EVX1

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 89/379 - (23%)
• Similarity: 138/379 - (36%)
• Gaps: 106/379 - (27%)

  Fly    30 VFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVS--KILNRYQETGSIRP------GV 86
            ||::|..|...:..::..::.:...|.....:..|..||:|  .:....:|.|...|      |:
Human     9 VFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGL 73

  Fly    87 IG-----GSKPKVT----------SPEIETRIDE---LRKENPSIFSWEIREKLIKE---GFAD- 129
            .|     |::|:|.          :|.:::...:   ...:..|.|..||......:   |.|:
Human    74 AGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEY 138

  Fly   130 PPSTSSISRLLRGSDRGSEDGRKDYTINGILGGRDSD--ISDTESEPGIPLKRKQRRSRTTFTAE 192
            ..|..|.|..|.||..|..:..|.   ||..||..|.  ::.:.|:       :.||.||.||.|
Human   139 QHSKGSGSEALVGSPNGGSETPKS---NGGSGGGGSQGTLACSASD-------QMRRYRTAFTRE 193

  Fly   193 QLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRAR--------------------- 236
            |:..||:.|.|..|.....|.|||....|.|..|:|||.|||.:
Human   194 QIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTY 258

  Fly   237 LRKHSGGSNSGL-------------SPMNSGSSNVGVGVG--LSGATAPLG-------------- 272
            :..|:..: .||             ||:..|:::......  .||:..||.
Human   259 MMSHAAAA-GGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPEL 322

  Fly   273 -----YGPLGVGSMAGYSPAPGTTATGAGMNDGVHHAAHAPSSHHSAATAAAAA 321
                 :.||..|      ||.|..|:..|....:  |.|:..::..|..||||:
Human   323 LCAFRHPPLYPG------PAHGLGASAGGPCSCL--ACHSGPANGLAPRAAAAS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	27/140 (19%)
		Homeodomain	183..239	CDD:459649	26/76 (34%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		15/90 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		13/44 (30%)
		Homeodomain	184..240	CDD:459649	26/55 (47%)