Protein Alignment gsb-n and Pitx2

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 347
• Identity: 84/347 - (24%)
• Similarity: 133/347 - (38%)
• Gaps: 102/347 - (29%)

  Fly   130 PPSTSSISRLLRGSDRGSEDGRKDYTINGILG--------------GRDSDISDTESEPGIPLKR 180
            |.:.:..|.|..|..|..:..:....::.|..              |::.|:...:...    |:
Mouse    30 PQALAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEVAEKDKGQQGKNEDVGAEDPSK----KK 90

  Fly   181 KQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGS- 244
            :|||.||.||::||:.||..|.|.:|||:.||||:|..|.|||||::|||.||||:.||.....
Mouse    91 RQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ 155

  Fly   245 ----NSGLSPMNSG------------SSNVGVGVGLSGATA---------PLGYGPLGVGSMAGY 284
                .:|..|..:|            |.|.....||:.|:.         .:...||...||  :
Mouse   156 AELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSM--F 218

  Fly   285 SPAPGTTATGAGMNDGVHHAAHAPSSHHSAATAAAAAHHHTQMGGYDLVQSAAQHGFPGGFAQPG 349
            ||                     |:|..|.:.:::            :|.||.. |.||.
Mouse   219 SP---------------------PNSISSMSMSSS------------MVPSAVT-GVPGS----- 244

  Fly   350 HFGSQNYYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAAANYNAHV 414
                        |..::::.:.|::.|::...|:  .:..|:....|..:......:.|:.....
Mouse   245 ------------SLNSLNNLNNLSSPSLNSAVPT--PACPYAPPTPPYVYRDTCNSSLASLRLKA 295

  Fly   415 AQHQLNDYAAAAAHGNPASAYS 436
            .||....||:..   ||||..|
Mouse   296 KQHSSFGYASVQ---NPASNLS 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	3/10 (30%)
		Homeodomain	183..239	CDD:459649	33/55 (60%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	33/55 (60%)
		OAR	282..299	CDD:461067	2/16 (13%)