Protein Alignment gsb-n and Pax8

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_035170.1
• Gene: Pax8 / 18510
• MGIID: 97492
• Length: 457
• Species: Mus musculus
• Alignment Length: 430
• Identity: 148/430 - (34%)
• Similarity: 199/430 - (46%)
• Gaps: 131/430 - (30%)

  Fly     7 NSLRPLFAGYPFQGQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSK 71
            ||:|        .|.|.:|||||.|:||||||..:|.:||::|..|||||.||||||||||||||
Mouse     4 NSIR--------SGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60

  Fly    72 ILNRYQETGSIRPGVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PPST 133
            ||.||.|||||||||||||||||.:|::..:|.:.:::||::|:||||::|:.||..|   .||.
Mouse    61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

  Fly   134 SSISRLLR-----------------------------GSDRGSEDGRKD-----YTINGILG--- 161
            |||:|::|                             .:....|..:.|     |:|||:||
Mouse   126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQ 190

  Fly   162 -GRDS----DISD-------TESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVY---- 210
             |.|:    |.||       .:|:......||..|: .||:...|||||..|.|..||:.|
Mouse   191 PGNDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DTFSQHHLEALECPFERQHYPEAYASPS 254

  Fly   211 -TREELA------QTTALTEARIQVWFSNR--RARLRKHSGG-------------------SNSG 247
             |:.|..      ..:||.:.:..:..||.  ...|..|...                   |:|.
Mouse   255 HTKGEQGLYPLPLLNSALDDGKATLTSSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPELSSSS 319

  Fly   248 LSPMNSGSS------NVGVGVGLSGATAP-------------------LGYGPLGVG-SMAGYSP 286
            .:|.:..||      .||.| |.:||:.|                   |..|...|| ::.||.|
Mouse   320 STPSSLSSSAFLDLQQVGSG-GPAGASVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPP 383

  Fly   287 APGTTATG-------AGMNDGVHHA----AHAPSSHHSAA 315
            ...|:..|       |||..|..::    :|.|.|.:|.|
Mouse   384 HIPTSGQGSYASSAIAGMVAGSEYSGNAYSHTPYSSYSEA 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	77/123 (63%)
		Homeodomain	183..239	CDD:459649	20/68 (29%)
Pax8	NP_035170.1	PAX	9..133	CDD:128645	77/123 (63%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	12..68		39/55 (71%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	87..135		19/47 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..224		16/64 (25%)
		Pax2_C	344..456	CDD:463563	20/80 (25%)