Protein Alignment gsb-n and Pax4

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_035168.1
• Gene: Pax4 / 18506
• MGIID: 97488
• Length: 349
• Species: Mus musculus
• Alignment Length: 363
• Identity: 131/363 - (36%)
• Similarity: 177/363 - (48%)
• Gaps: 58/363 - (15%)

  Fly    20 GQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIRP 84
            |...||||||:|:||||||...|.:||::|..|:|||.|||.|:||:|||||||.||..||.:.|
Mouse     5 GLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEP 69

  Fly    85 GVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFA---DPPSTSSISRLLRGSDRG 146
            ..||||||::.:|.:..||.:|:.|.|::|:|||:.:|..||..   ..||.|||:|:||..
Mouse    70 KCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRAL--- 131

  Fly   147 SEDGRKDYT-------INGILGGRDSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRT 204
            .||....:|       :..:|....|:.    ..|..|......|:||.|:..|.||||:.|.|.
Mouse   132 QEDQSLHWTQLRSPAVLAPVLPSPHSNC----GAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRG 192

  Fly   205 QYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHS---------GGSNSGLSPMNSGSSNVGV 260
            ||||...|.:||..|:|.|..::||||||||:.|:..         |.|.....|.||      .
Mouse   193 QYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNS------P 251

  Fly   261 GVGLSGATAPLGYGPLGVGSMAGYSPAPGT-------TATGAGMNDGVHHAAHAP---------- 308
            |: :|...:|   |.:...::....|...:       ||.|...:|....|...|
Mouse   252 GI-ISAQQSP---GSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPV 312

  Fly   309 --SSHHSAATAAAAAH--HHTQMGGYDLVQSAAQHGFP 342
              ||:...|......|  ||. :||...|.|.....:|
Mouse   313 ASSSYVEFAWPCLTTHPVHHL-IGGPGQVPSTHCSNWP 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	65/123 (53%)
		Homeodomain	183..239	CDD:459649	29/55 (53%)
Pax4	NP_035168.1	PAX	5..129	CDD:128645	65/123 (53%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		36/55 (65%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		20/47 (43%)
		Homeodomain	172..227	CDD:459649	29/54 (54%)
		Transcription repression	278..349		16/71 (23%)