Protein Alignment gsb-n and Pax3

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 203/483 - (42%)
• Similarity: 251/483 - (51%)
• Gaps: 96/483 - (19%)

  Fly    14 AGYPFQ-----GQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKIL 73
            :|:|.:     |||||||||||||||||||||||.||||||..|:||||||||||||||||||||
  Rat    23 SGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKIL 87

  Fly    74 NRYQETGSIRPGVIGGSKPK-VTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PPSTS 134
            .|||||||||||.||||||| ||:|::|.:|:|.::|||.:||||||:||:|:...|   .||.|
  Rat    88 CRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVS 152

  Fly   135 SISRLLR-----GSDRGSEDGRKD---------YTINGILGGRDS-----DISDTESEPGIPLKR 180
            ||||:||     |.:..::..||:         ::|:|||..|.|     :.||.:|||.:||||
  Rat   153 SISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKR 217

  Fly   181 KQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGSN 245
            |||||||||||||||.|||||.||.|||:||||||||...|||||:||||||||||.||.:|.:.
  Rat   218 KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQ 282

  Fly   246 SGLSPMNSGSSNVGVGVGLSGATAPLGYGPLGVGSM-------AGYSPAPGTTATGAGMNDGVHH 303
              |...|.              ..|.|:.|..:.::       ..|.|.            .:..
  Rat   283 --LMAFNH--------------LIPGGFPPTAMPTLPTYQLSETSYQPT------------SIPQ 319

  Fly   304 AAHAPSS--HHSAATAAAAAHHHTQMGGYDLVQS----AAQHGF---------PGGFAQP----- 348
            |...|||  |.......:..|..|.....|...:    :.:|||         |.|.:.|
  Rat   320 AVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAI 384

  Fly   349 -------------GHFGSQNYYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWS 400
                         .|.|..:....||:...:....:.|....:..|..|....|...|.....:.
  Rat   385 GNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYC 449

  Fly   401 QAAYHAAANYNAHVAQHQLNDYAAAAAH 428
            ...|.........|..:|...|..:|.|
  Rat   450 PPTYSTTGYSMDPVTGYQYGQYGQSAFH 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	94/124 (76%)
		Homeodomain	183..239	CDD:459649	46/55 (84%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	94/124 (76%)
		Homeodomain	220..276	CDD:459649	46/55 (84%)
		Pax7	347..391	CDD:403540	7/43 (16%)