DRSC/TRiP Functional Genomics Resources

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Protein Alignment gsb-n and phox2a

DIOPT Version :10

Sequence 1:NP_523862.1 Gene:gsb-n / 38004 FlyBaseID:FBgn0001147 Length:449 Species:Drosophila melanogaster
Sequence 2:NP_001239128.1 Gene:phox2a / 100486496 XenbaseID:XB-GENE-853857 Length:281 Species:Xenopus tropicalis


Alignment Length:246 Identity:87/246 - (35%)
Similarity:111/246 - (45%) Gaps:51/246 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 TINGILGG-RDSDISDTESEP--------GIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVY 210
            |.|..||. ||...|...:.|        ||..||||||.|||||:.||:.|||.|:.|.|||:|
 Frog    56 TANCTLGALRDHQPSPYSTVPYKFFSDPSGINEKRKQRRIRTTFTSSQLKELERVFAETHYPDIY 120

  Fly   211 TREELAQTTALTEARIQVWFSNRRARLRKHSGGSNSGLSPMNSGSSNVGVGVGLSGATAPLGYGP 275
            ||||||....|||||:||||.||||:.||....:||     .|||||.| |.| :..:.|.....
 Frog   121 TREELALKIDLTEARVQVWFQNRRAKFRKQERAANS-----KSGSSNNG-GSG-NKKSDPRSSSE 178

  Fly   276 LGVGSMAGYSPAPGTTA---TGAGMNDGVHHAAHAPSSHHSAATAAAAAHHHTQMGGYDLVQSAA 337
            ......:..||.|.:||   |...:|......:.:|    .|.:...:||         .||:..
 Frog   179 DDESKESNCSPTPDSTASLPTAGNLNSPGGSLSPSP----GAVSGLVSAH---------TVQALK 230

  Fly   338 QHGFPG------------------GFAQPGHF-GSQNYYHQDYSKLTIDDF 369
            ...:||                  ..|.||.| |..:.:|:..:.|..:.|
 Frog   231 GPAWPGVPTSSSTSTAELLKAWQPAEAVPGPFAGVLSTFHRKPNTLKANLF 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gsb-nNP_523862.1 HTH_CRP 20..141 CDD:481199
Homeodomain 183..239 CDD:459649 37/55 (67%)
phox2aNP_001239128.1 Homeodomain 93..149 CDD:459649 37/55 (67%)
Blue background indicates that the domain is not in the aligned region.

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