Sequence 1: | NP_523862.1 | Gene: | gsb-n / 38004 | FlyBaseID: | FBgn0001147 | Length: | 449 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001280727.1 | Gene: | DUX4 / 100288687 | HGNCID: | 50800 | Length: | 424 | Species: | Homo sapiens |
Alignment Length: | 328 | Identity: | 88/328 - (26%) |
---|---|---|---|
Similarity: | 116/328 - (35%) | Gaps: | 91/328 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 171 ESEPGIPLKR---KQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSN 232
Fly 233 RRARLRKHSGGSNSGLSPMNSGS------------------SNVGV-GVGLSGATAPLGYGPLGV 278
Fly 279 GSMAGYS--PAPGTTATGAGMNDGVHHAAHAPSSHHSAATA---AAAAH-------HHTQMGGYD 331
Fly 332 LVQSAAQHGFPG--GFAQPG--HFGSQNYYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSK 392
Fly 393 LEAPSNWSQAAYHAAANYN-----AHVAQHQLNDYAAAAAHGN------PASAYSHPLPTQGQAK 446
Fly 447 YWS 449 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
gsb-n | NP_523862.1 | PAX | 20..141 | CDD:278709 | |
Homeobox | 185..238 | CDD:278475 | 27/52 (52%) | ||
DUX4 | NP_001280727.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..24 | ||
Homeobox | 27..74 | CDD:306543 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 72..102 | 9/21 (43%) | |||
Homeobox | 97..149 | CDD:306543 | 27/54 (50%) | ||
DNA_pol3_gamma3 | <141..319 | CDD:331207 | 47/211 (22%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 218..362 | 35/172 (20%) | |||
Required for interaction with EP300 and CREBBP, and for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:26951377 | 327..424 | 12/47 (26%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..414 | ||||
Important for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:29618456 | 405..424 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0849 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |