DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zip and XI-I

DIOPT Version :9

Sequence 1:	NP_523860.2	Gene:	zip / 38001	FlyBaseID:	FBgn0265434	Length:	2056	Species:	Drosophila melanogaster
Sequence 2:	NP_001328260.1	Gene:	XI-I / 829456	AraportID:	AT4G33200	Length:	1523	Species:	Arabidopsis thaliana

Alignment Length:	1415	Identity:	422/1415 - (29%)
Similarity:	637/1415 - (45%)	Gaps:	349/1415 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 VWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDIQKMNP--PKFDKVEDMAELTCLNE 144
            |||..::..::||.:.....:::.|| ..|||:|.:..:.:.:.:|  .:.:.|:||.:||.|:|
plant    17 VWVEDKDLAWIAADVLDSFDNKLHVE-TSTGKKVFVSPEKLFRRDPDDEEHNGVDDMTKLTYLHE 80

  Fly   145 ASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLP-IYTEKIMERYKGIKRHEVPPHVFAITDSAY 208
            |.||:|::.||....||||:|...:.|||:|||| :|...:||:|.|....|:.|||||::|.||
plant    81 AGVLYNLQRRYALNDIYTYTGSILIAVNPFKKLPHLYNGHMMEQYMGAPFGELSPHVFAVSDVAY 145

  Fly   209 RNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIK 273
            |.|:.|...||||.:|||||||||.||.::|:|.:|..
plant   146 RAMIDDSRSQSILVSGESGAGKTETTKLIMQYLTFVGG--------------------------- 183

  Fly   274 VKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIR 338
               .|.:.::::                    |||:|::||:||||||||||:||||||||||:.
plant   184 ---RATDDDRSV--------------------EQQVLESNPLLEAFGNAKTVRNDNSSRFGKFVE 225

  Fly   339 INFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLSN 403
            |.||.:|.||||.|.|||||:||.:|....||.:|.||||.|..  ...||:.|.:.:.:.:|:.
plant   226 IQFDTNGRISGAAIRTYLLERSRVVRITDPERNYHCFYQLCASG--NDAEKYKLSNPRQFHYLNQ 288

  Fly   404 G-SLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPD-- 465
            . :..:.||....|::.|.::|:|:|::.::...|||.::|:|..|:::|...|.:|.:.:.|
plant   289 SKTYELEGVSSAEEYKNTRRAMDIVGISQDEQEGIFRTLAAILHLGNVEFSSGREHDSSVVKDPE 353

  Fly   466 -NTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVN 529
             ....|..|.|.......:..:..|..|......:.||........:.:.:||..|..:|.|||:
plant   354 SRHHLQMAADLFKCDANLLLASLCTRSILTREGIIIKALDPNAAVTSRDTLAKTVYAHLFDWLVD 418

  Fly   530 RINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 594
            :||:|:.:.. :....||:||:.|||.|:.|||||.|||:.||||||.||..:|.:||:||::|.
plant   419 KINKSVGQDP-ESRFQIGVLDIYGFECFKNNSFEQFCINFANEKLQQHFNEHVFKMEQDEYRKEE 482

  Fly   595 IEWKFIDFGLDLQPTIDLID-KPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRG 658
            |.|.:|:| :|.|..:|||: ||.|::|||||.|.||::|.::|..||......||:..|..| .
plant   483 INWSYIEF-IDNQDVLDLIEKKPIGVIALLDEACMFPRSTHESFSMKLFQNFRFHPRLEKPKF-S 545

  Fly   659 VADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQ 723
            ..||.:.||||:|.|....:|.||.|.......:||..|:.|||..|:..      |.:..|.:.
plant   546 ETDFTLSHYAGKVTYQTEAFLDKNRDYTIVEHCNLLSSSKCPFVAGIFPS------APEESTRSS 604

  Fly   724 FGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVL 788
            :       .|.:||..:|:||..||:||..|.|::|||:.||...|..|.::..||.||||.|||
plant   605 Y-------KFSSVSSRFKQQLQALMETLSKTEPHYVRCVKPNSLNRPQKFESLSVLHQLRCGGVL 662

  Fly   789 EGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFF 853
            |.:||...|:|.|..:.:|..|:.||.|..:.:. .|.:...||::..|.|.:  |::|::|:|.
plant   663 EAVRISLAGYPTRRNYSDFVDRFGLLAPEFMDES-NDEQALTEKILSKLGLGN--YQLGRTKVFL 724

  Fly   854 RAGVLAHLEEERDFKISD----LI--------------------VNFQAFCRGFLARRNYQKRLQ 894
            |||.:..|:..| .::.|    ||                    ::.||:|||.|:|..|..|
plant   725 RAGQIGILDSRR-AEVLDASARLIQRRLRTFVTHQNFISARASAISIQAYCRGCLSRNAYATR-- 786

  Fly   895 QLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQ 959
                     ||.||.:                          |||     |.||..|.
plant   787 ---------RNAAAAV--------------------------LVQ-----KHVRRWLS------- 804

  Fly   960 EYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLAL 1024
                  :.|.|:..:.|..||:    |..|:.:|.:...:|                 |.|..:|
plant   805 ------RCAFVKLVSAAIVLQS----CIRADSTRLKFSHQK-----------------EHRAASL 842

  Fly  1025 GGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEED--------LALTDDQNQKLL 1081
                                            :|...:|.|:...        :|:.....|||.
plant   843 --------------------------------IQAHWRIHKFRSAFRHRQSSIIAIQCRWRQKLA 875

  Fly  1082 K-EKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIET 1145
            | |.:.|::.||         |..|..|||.|         ||:||.
plant   876 KREFRKLKQVAN---------EAGALRLAKTK---------LEKRLE------------------ 904

  Fly  1146 EVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDL 1210
               ||            |.:.||.||        ||...|.|..:...|.|:.|||...::.
plant   905 ---DL------------EWRLQLEKR--------LRTSGEEAKSSEISKLQKTLESFSLKLD--- 943

  Fly  1211 EAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEG 1275
                |||         |:...|..||.:|:              ::.:::..:||..|
plant   944 ----AAR---------LATINECNKNAVLE--------------KQLDISMKEKSAVE------- 974

  Fly  1276 VLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQA 1340
                      :|||.    :..|:|...:|:.:..:||.:|..|..||.:..::.....::.|:|
plant   975 ----------RELNG----MVELKKDNALLKNSMNSLEKKNRVLEKELLNAKTNCNNTLQKLKEA 1025

  Fly  1341 ESQIAELQVKLAEIERARSELQEKCTKLQQEA-----ENITNQLEEAELKASAAVKSASNMESQL 1400
            |.:.:|||..:..:|...|.|:.:...|.|:.     |.|...|  .|.|.|:||..|.|....:
plant  1026 EKRCSELQTSVQSLEEKLSHLENENQVLMQKTLITSPERIGQIL--GEQKHSSAVVPAQNDRRSV 1088

  Fly  1401 TEA----------QQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDE 1440
            .|.          ...|.|..|.||.....|...|.....::|.|..:|:
plant  1089 FETPTPSKHIMPFSHSLSESRRSKLTAERNLENYELLSRCIKENLGFNDD 1138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	80..117	CDD:280832	11/34 (32%)
		Myosin_head	133..854	CDD:278492	277/726 (38%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	270/714 (38%)
		Myosin_tail_1	931..2011	CDD:279860	112/534 (21%)
		Prefoldin	1431..1515	CDD:298833	3/10 (30%)
		FAM76	<1847..1926	CDD:292665
XI-I	NP_001328260.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000014
OrthoInspector	1	1.000	-	-		mtm946
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910