|
Fly 76 WTQKRLVWVPHENQGFVAASIKRE-HGDEVEVELAETGKRVMILRD-DIQKMNPPKFDKVEDMAE 138
|..|:.||||.|...:|.|.:|.| .|..|.||..: ::|:::|: ::|.||||:||.:||||.
Human 71 WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKD--QKVLMVREAELQPMNPPRFDLLEDMAM 133
Fly 139 LTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVPPHVFAI 203
:|.|||||||||::.||...:||||||||||.:||||.||:||..::..|||.:|.:.|||::|:
Human 134 MTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAV 198
Fly 204 TDSAYRNMLGD--REDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSV 266
.|:||.:||.. |.|.|.....:.|.|: .:|...|
Human 199 ADNAYNDMLRSKGRLDSSPTADPDLGPGR-----------------------PLPRQPV------ 234
Fly 267 NTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSS 331
...:|.:....| |.||.|:::|||.:||||||||::|||||
Human 235 ------------HADHQFLATKTG------------GTLEDQIIEANPAMEAFGNAKTLRNDNSS 275
Fly 332 RFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILD-DV 395
||||||||:|..||.::.|:|::|||||||.|.|...||::|::||:|:|..||.::..:|. :.
Human 276 RFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNP 340
Fly 396 KSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQ 460
..|.|.|.|.:.|..::|..|..||..:|:|:|.:.::..:.::||.|:|.||:|||:|::..:|
Human 341 YDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQ 405
Fly 461 ATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFK 525
|.......|.|.|:|:|:|..|:.:..|.||::||.::|||.|:.|||.|||.|:|||.|:|:|:
Human 406 AEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFR 470
Fly 526 WLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 590
|||:|||::|| ||.....|||:||:|||||||.|||||||||:|||||||.||..||:||||||
Human 471 WLVSRINQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEY 534
Fly 591 QREGIEWKFIDFGLDLQPTIDLIDK--------------------PGGIMALLDEECWFPKATDK 635
:||||:|.||||||||||.||||:| |.||:::|:|||.||||:|.
Human 535 KREGIDWVFIDFGLDLQPCIDLIEKVRRLRLSDVGGPHSYSFCSQPLGILSILEEECMFPKASDA 599
Fly 636 TFVDKLVSAHS-MHPKFM------KTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSL 693
:|..||...|: ..|.|. |..:: |.|.:|||||.|.||...||.||.|||||.:|.:
Human 600 SFRAKLYDNHAGKSPNFQQPRPDKKRKYQ--AHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPI 662
Fly 694 LQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGA----RTRKGMFRTVSHLYKEQLAKLMDTLRNT 754
.|.||:..:..:::: .|....|:..... |.:...|:|||.|:||.|.|||..||.|
Human 663 FQKSQNRLLATLYEN-----YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRAT 722
Fly 755 NPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVI 819
.|:|||||:||..|..|.:||.|||.|||||||||||||||||||||:.:.:|||||.:|.|:.|
Human 723 QPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAI 787
Fly 820 PKG-FMDGKKACEKMIQALELDSNLYRVGQSK--------------------------------- 850
|.. |||.:||.||::.:|:||...|:.|.:|
Human 788 PDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVGALWDQGWPWLWRSHWAGFMRMVGGYPGCLPL 852
Fly 851 ---IFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKL 912
:||:||:|..|||.||.:::.::...||..||.|.|..||:.|...:|:..||.|..|:..:
Human 853 RPQVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAV 917
Fly 913 RNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAE 977
:||.|.:|:.|:||||...:.||:|.....||:.:|..|.......||.|..:.....||..||.
Human 918 KNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLAL 982
Fly 978 QLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQL 1042
|||||.:..|:|||....|:..|.:||..::||..|:|:|||....|...::|||....:|::.:
Human 983 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1047
Fly 1043 EEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKH 1107
::.|....|.:.||...:.|:|...|::|..|:...:|.||||.|:|........|..||::...
Human 1048 DDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSA 1112
Fly 1108 LAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKRE 1172
|.|.|.:.|..:.:||..|.::::.|.:::|:|||:|.::...:|.:.:......:::.:|.|::
Human 1113 LTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKD 1177
Fly 1173 EELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNE 1237
.||:|..||:::|....|..||..:||:::..|::|:||||:||||:.||.|.:.:.|||.|...
Human 1178 SELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1242
Fly 1238 LLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAK 1302
|.::...:|.|:|...|||.||..|::.|||..:.||..:|.:|.|.::....:.:|:::|::.:
Human 1243 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVR 1307
Fly 1303 TVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTK 1367
..|||.|..|..|..|||..:.::..::...::..:..|.|::|.::|:.|::|..::...:..:
Human 1308 QKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGR 1372
Fly 1368 LQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQ 1432
||.|:..::..|||.|...|...:..:.....|.|.::.||||::.|..|:..::.:..:.:.|:
Human 1373 LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLR 1437
Fly 1433 EQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDA-DLAKELEEGKKRLNKDIEALERQVKELIA 1496
||.||:.||:...:|.|::...::.:.:.|.|.|| ...:||||.||:|...::..|..|:...|
Human 1438 EQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1502
Fly 1497 QNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREA 1561
:...|:|:|.::|:|.||.|:|||...:....|:|||::.::.|.|.:...|::.:|.:.|:||:
Human 1503 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRES 1567
Fly 1562 REKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAE 1626
|...|::..:....:||.:.:|.|:.:.|.||.|:.||.:....:.|::.||||.|:|||.:.:|
Human 1568 RGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSE 1632
Fly 1627 LKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEE 1691
::|..||.|..|:|.|...||:::.:..::::.:|.|..|:|.....||...:.:..|:..||.|
Human 1633 IQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAE 1697
Fly 1692 RKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKD--ALRDAEEAKAAK--E 1752
.:.|..|:..|||:||||.::|..:....:...:|....:.:|||:|: |.||.|:..||: |
Human 1698 TRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHE 1762
Fly 1753 ELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAE--EIANNANKGSLMIDEKR 1815
:.||| ||:...|.||:.:|...|...||:||.||.|..|..| .:.::.|.| ::::|:
Human 1763 QAQAL----ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG--LLNQKK 1821
Fly 1816 RLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKEL 1880
:|||.:|.|..|:||.........::::||......:..||..|:..|...|..:..||:..:||
Human 1822 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVREL 1886
Fly 1881 KAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDER 1945
:|:|.|.|.|.....|..:..||||:..||.:|:.|.|:.....|..||.::::|||....|::|
Human 1887 QARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDR 1951
Fly 1946 RHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTK 2010
:::.:.::.:|||.|::|..||..:|.|::......:.||.|.|.:|..|..:....:.|.|:.:
Human 1952 KNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRAR 2016
Fly 2011 LRRTGGIGLSSS 2022
.|...|..||.|
Human 2017 TRDALGPKLSLS 2028
| 
