Protein Alignment zip and myh7bb

DIOPT Version :9

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0265434
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: XP_009295034.2
• Gene: myh7bb / 560945
• ZFINID: ZDB-GENE-090311-5
• Length: 1935
• Species: Danio rerio
• Alignment Length: 1980
• Identity: 737/1980 - (37%)
• Similarity: 1180/1980 - (59%)
• Gaps: 83/1980 - (4%)

  Fly    62 VERNQFNDPATQAEWTQ-------------KRLVWVPHENQGFVAASIKREHGDEVEVELAETGK 113
            :|..:|.:.||....|.             |:.||:|.|.:.::...||...||:|.|| .:.|:
Zfish     5 MELREFGEAATFLRKTNLEQLAAQSHAFDGKKRVWIPDEKEAYIEVEIKDTDGDKVMVE-TKDGR 68

  Fly   114 RVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLP 178
            .:.:..:|||:|||||||.:||||.||.|||||||.|:..||...:||||||||||.|||||.||
Zfish    69 MLTVKEEDIQQMNPPKFDLMEDMAMLTHLNEASVLFNLSRRYSFWMIYTYSGLFCVTVNPYKWLP 133

  Fly   179 IYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAY 243
            :|:.:::..|||.:|.:||||:::|.|:||.:||.:||:||:|.|||||||||.|||:|||:.|.
Zfish   134 VYSSEVVAAYKGKRRSDVPPHIYSIADNAYNDMLKNRENQSMLITGESGAGKTVNTKRVIQYFAI 198

  Fly   244 VAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQ 308
            :||....|                                      |.|         .|.||.|
Zfish   199 IAALGEAG--------------------------------------GKK---------GGTLEDQ 216

  Fly   309 LLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFH 373
            :::|||.:||||||||::|||||||||||||:|..:|.::.|:|:.|||||||.|.|...||::|
Zfish   217 IIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDIYLLEKSRVIFQQTGERSYH 281

  Fly   374 IFYQLLAGATPEQREKFIL-DDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSI 437
            |:||:|:...||.::..:: .:...|.|.|.|.:.|..:||..|..||..:|:.:|.|.|:....
Zfish   282 IYYQILSHRKPELQDMLLVSSNPFDYHFCSQGVITVDNMDDGDELLATDHAMDTLGFTPEEKYGC 346

  Fly   438 FRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKA 502
            ::||..::.||:|||:.::..:||.......|.|.::|:|:|..|:.:..|.||:|||.:::.:.
Zfish   347 YKIVGGIMHFGNMKFKVKQREEQAEADGTESADKASYLMGISSADLIKGLLHPRVKVGNEYIVRG 411

  Fly   503 QTKEQVEFAVEAIAKACYERMFKWLVNRINRSL-DRTKRQGASFIGILDMAGFEIFELNSFEQLC 566
            ||.|||.:||.|:|||.|:|||||||.|||::| ....||  .|||:||:|||||||.|:|||:|
Zfish   412 QTVEQVTYAVGALAKATYDRMFKWLVGRINKTLYTAIPRQ--FFIGVLDIAGFEIFEFNNFEQMC 474

  Fly   567 INYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPK 631
            ||:|||||||.|||.|||||||||:.|||||.|||||||||..||||:||.||:::|:|||.|||
Zfish   475 INFTNEKLQQFFNHHMFILEQEEYKTEGIEWTFIDFGLDLQACIDLIEKPLGILSILEEECMFPK 539

  Fly   632 ATDKTFVDKLV-SAHSMHPKFMK--TDFRGVAD--FAIVHYAGRVDYSAAKWLMKNMDPLNENIV 691
            ||:.:|..||. :.....|.|:|  .|.:...|  |.:|||||.|.|:...||.||.|||||.:|
Zfish   540 ATESSFKAKLYDNLLGKSPNFLKPRPDKKRKYDTHFELVHYAGVVPYNINGWLDKNRDPLNETVV 604

  Fly   692 SLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKG-MFRTVSHLYKEQLAKLMDTLRNTN 755
            .:.|.|.:..:.:::::...:....:|...::  .:.:|| .|:|||.|:||.|.|||..||:|.
Zfish   605 GIFQRSSNKLMSSLFENFISLDSGSEAKPGSK--EKRKKGASFQTVSQLHKENLNKLMTNLRSTQ 667

  Fly   756 PNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIP 820
            |:||||||||..|..|.::..|||.|||||||||||||||:||||||.:.||:|||.:|.|..||
Zfish   668 PHFVRCIIPNEAKNPGMMEPFLVLHQLRCNGVLEGIRICRKGFPNRILYAEFKQRYRILNPLAIP 732

  Fly   821 KG-FMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFL 884
            :. ::|.:||.||::.:|::|...|:.|.||:||:||:|..||:.||.::|.::...||||||.|
Zfish   733 EDTYVDSRKAVEKLLGSLDIDHTQYKFGHSKVFFKAGLLGQLEDMRDERLSKVLTLLQAFCRGKL 797

  Fly   885 ARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVRE 949
            .|...::.:::..|:.:||.|..|:..::||.|..|:.|:||||.....|::|...::|.::::|
Zfish   798 MRMERKRMMKEKEALMVIQWNIRAFYAVKNWPWMCLFFKIKPLLRSAATEKELATLKEEFQKLKE 862

  Fly   950 KLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRI 1014
            .|:......:|.|.|....:.||..|:.|||||.:..|:||:..:.|:..|.::|..::||..|:
Zfish   863 ALERSEVKRKELEEKQVSLVQEKNDLSLQLQAEQDNLADAEDRCNLLIKAKIQMEGKIKELMERL 927

  Fly  1015 EEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQK 1079
            |:|||....:..:|:|||....:|::.|::.|....|::.||...:.|:|...|::|..|:...:
Zfish   928 EDEEEMNATILAKKRKLEDECIELKKDLDDLEITLAKVEKEKHATENKVKNLVEEMAALDETISR 992

  Fly  1080 LLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIE 1144
            |.||||.|::......:.|..||.|...|:|.|.|.|..:.:||..|.::::.|.:.:|.|||:|
Zfish   993 LSKEKKALQDAHQQALEDLQSEENKVNMLSKAKIKLEQQVDDLEGSLEQEKKVRMDLERVKRKLE 1057

  Fly  1145 TEVADLKEQLNERRVQVD----EMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAE 1205
               .|||..: |..:.:|    :::.:|.|::.|:.|...:|:||.|......|..:||::::.|
Zfish  1058 ---GDLKLSV-ESSMDLDNSKQQLEERLKKKDHEMVQIGAKIEEEQALVIQLHKKIKELQTRIEE 1118

  Fly  1206 IQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEET 1270
            ::|:||||:|||:|:||.|.|:|.|||.|...|.::...|.||.|:..|||.:...|::.|||.:
Zfish  1119 LEEELEAERAARSKSEKQRSDVSRELEELSERLEEAGGATTAQIEMNKKREADFIKLRRDLEEAS 1183

  Fly  1271 VNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDR 1335
            ::||..:|.:|.||:..:..:.:||:||::.|..|||.|.....|..|||:.:..::.::...::
Zfish  1184 LHHETTIAMLRRKHADTVAEMGEQLDNLQRVKQKLEKEKAETRMECEDLASNVEHLSRAKTTTEK 1248

  Fly  1336 RRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQL 1400
            ..:..|.|:.|.:.|:.|::|...::..:..:.|.|:..::.:|||.|:......::.......:
Zfish  1249 MCRMYEDQLNESKTKIEELQRQLMDVTSQKARAQTESAEVSRRLEEKEVLVMQLQRTKIAFSQTV 1313

  Fly  1401 TEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEE 1465
            .|.::.||||::.|..|:..::....:.:.|:||.||:.|||...:|.|::...::.:.:.|.|.
Zfish  1314 EELKKQLEEESKAKNSLAHAVQSSRHDCDLLREQFEEEQEAKSELQRALSKANIEIAQWRTKYET 1378

  Fly  1466 DA-DLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLEL 1529
            || ....|||:.||:|...::..|..|:...|:...|:|:|.::|:|:||..::||......:.|
Zfish  1379 DAIQRTDELEDAKKKLVARLQGSEEAVEASNAKCASLEKTKHRLQTEIEDLMVDLERSNAVAIAL 1443

  Fly  1530 EKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQN 1594
            :|||:||||:|:|.:...|:...|.:.:::|:|...|::..:....:||.|::|.::.:.|.||.
Zfish  1444 DKKQRNFDKVLSEWRQKFEETQSELEGSQKESRSLSTELFKLKNSYEEALDQLETIKRENKNLQE 1508

  Fly  1595 ELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQF 1659
            |:.||.:.....:|.:||||:.|:.|:.:..:::|..||.|..|:..|...||:::.:...:::.
Zfish  1509 EITDLTDQISQGNKTIHELEQMKKVLDHEKCDIQAALEEAEGTLEHEESKTLRVQLELSQTKTEV 1573

  Fly  1660 ERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKE 1724
            |:.|..::|..:..||...:.|..::|.||.|.:.|..|:..|||:|.|:.|:|..:...|:...
Zfish  1574 EKKLAERDEEIDNLRRNHQRTLEGMQTTLDAETRARNEAIRVKKKMENDMNEMEIHLNHANRQAV 1638

  Fly  1725 DALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAA 1789
            ::.|..:.||.|:||...:.:|:....|||:......||:...|.||:.:|......::|.|:.|
Zfish  1639 ESQKMVRNLQLQIKDLQVELDESMHHCEELKEQVAVTERRNTLLSAELEELRGVAEQTDRMRKVA 1703

  Fly  1790 ETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTT 1854
            |.|..|.:|.:.....:.::|:::|::||:.::.|..|:::.|.......::::||......:..
Zfish  1704 EHELLESSERVNLLHAQNTVMLNQKKKLESDLSMLSGEVDDAQQECRNAEEKAKKAITDAAMMAE 1768

  Fly  1855 ELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKE 1919
            ||..|:..|...|..:..:|:..|:|:.:|.|.|.......|..|..:|.::..||.:|:.|.|:
Zfish  1769 ELKKEQDTSSHLERMKRNMEQTIKDLQNRLDEAEQIALKGGKKQIQKMEIRVRELETELDCEQKK 1833

  Fly  1920 RLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKR 1984
            ....||..||.:::|||||...|::|:.:.:.::.:|||.:::|..||..::.||::....|:.|
Zfish  1834 SAEFQKGIRKYERRIKELTYQTEEDRKTLLRMQDLIDKLQAKVKSFKRQAEDAEEQVNCNMTRFR 1898

  Fly  1985 KYQRECEDMIESQEAMNREINSLKTKLRRT 2014
            |.|.:.::..|..:....::|.|:.:.|.|
Zfish  1899 KIQHDLDEAEERADMAESQVNKLRVRTRET 1928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	80..117	CDD:280832	12/36 (33%)
		Myosin_head	133..854	CDD:278492	354/729 (49%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	345/717 (48%)
		Myosin_tail_1	931..2011	CDD:279860	322/1084 (30%)
		Prefoldin	1431..1515	CDD:298833	29/84 (35%)
		FAM76	<1847..1926	CDD:292665	20/78 (26%)
myh7bb	XP_009295034.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D47111at2759
OrthoFinder	1	1.000	-	-		FOG0000014
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100110
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X58
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720