Protein Alignment zip and myo15aa

DIOPT Version :10

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: XP_073801013.1
• Gene: myo15aa / 560592
• ZFINID: ZDB-GENE-080425-2
• Length: 4207
• Species: Danio rerio
• Alignment Length: 1081
• Identity: 339/1081 - (31%)
• Similarity: 510/1081 - (47%)
• Gaps: 217/1081 - (20%)

  Fly     9 KSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSV---------ER 64
            :|:|...|.....::||:..||            :.|:...:.|:..:.:|..|         .:
Zfish  1688 QSESPSSPFLGSALTNINLRKA------------SYKLPSTLGRSPDDPRYAVVTPQIQGEHWAQ 1740

  Fly    65 NQFNDPATQAE-WTQKRLVWVPH---------------ENQGFVAASIKREHGDEVEV------E 107
            ||..||....: |:.:|:  :||               |.:.||...:..:..|..|.      |
Zfish  1741 NQIIDPHEPDDVWSSERV--LPHHTVQNLTKWSMYRDEELENFVIPVLPGQETDSAEPAWLPDRE 1803

  Fly   108 LAETGK-----------RVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIY 161
            ....|.           ..|:.|:..::      |.||||.:|..|:|.:||.|:|.|:...|||
Zfish  1804 GEPQGNWYDKMYSIRSLPTMLYRERAEE------DGVEDMTQLEELHEGAVLLNLKKRFERNLIY 1862

  Fly   162 TYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGES 226
            ||.|...|.|||||...||...::.::||....|.|||:|||.:::|..|:..:|:|.|:.:|||
Zfish  1863 TYIGSILVSVNPYKMFNIYGTDMVLQHKGHALGENPPHLFAIANASYTKMMDAKENQCIIISGES 1927

  Fly   227 GAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGL 291
            |:||||.||.|:::||           |:.|                      .||.|
Zfish  1928 GSGKTETTKLVLRYLA-----------AIHH----------------------KQNIT------- 1952

  Fly   292 KMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYL 356
                           ||:|:|.|:||:|||||||:|||||||||::.| |...|.||||....||
Zfish  1953 ---------------QQILEATPLLESFGNAKTVRNDNSSRFGKYMEI-FMEEGVISGAITSQYL 2001

  Fly   357 LEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYAFLS-NGSLPVPGVDDYAEFQAT 420
            |||||.:.||||||.:||||::|||...:|::.|.|.|.::|.:|: .|...:.|..|..:|:..
Zfish  2002 LEKSRIVFQAKDERNYHIFYEMLAGLPSQQKQSFYLQDAETYYYLNQGGDCVIVGKSDGEDFRRL 2066

  Fly   421 VKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQ--ATLPDNTVAQKIAHLLGLSVTDM 483
            :.:|.|:..::||.:.|||::|::|..|::.|.:.....|  |::......:.:|.||.:|...:
Zfish  2067 LSAMEILHFSAEDQSGIFRVLSSILHLGNVFFERYETESQEVASVVSAQEIRVVAELLQISPEGL 2131

  Fly   484 TRAFLTPRIKVGRDFVTKAQTKEQVEFAV---EAIAKACYERMFKWLVNRINRSLDRTKRQGASF 545
            .::.   ..||......|..|...||.|:   :|:||..|..:|.||.:|||:.:  ..|..|..
Zfish  2132 QKSI---TFKVTETMREKIYTPLTVESAIDARDAVAKILYSLLFSWLTDRINKQV--YPRNEALS 2191

  Fly   546 IGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTI 610
            |.|||:.|||....||||||||||.||.||..||..:|..||:||.||.|.|:.:.|. |.|..|
Zfish  2192 ISILDIYGFEDLTFNSFEQLCINYANEYLQFFFNRVIFKEEQDEYNREQIIWEEVPFS-DNQACI 2255

  Fly   611 DLI-DKPGGIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYS 674
            ||| .||.||:.:||::..||:|||.||:.|....|..:|.:.|... .:.:|.|.||||:|.|.
Zfish  2256 DLIAAKPHGILRILDDQSGFPQATDHTFLQKCHYHHGNNPLYSKPKM-PLPEFTIKHYAGKVSYQ 2319

  Fly   675 AAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKD-AEIVGMAQQALTDTQFGAR---TRKGMFRT 735
            ..|:|.||.|.:.::::.|...|::..|..::.: ||.:...:     :|.|..   ||:....|
Zfish  2320 VHKFLDKNYDQVRQDVLDLFIQSKNKMVAYLFMNYAEALNQQR-----SQIGKNSTVTRRHQAST 2379

  Fly   736 VSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPN 800
            |:..:::.|.:|::.:...||.|||||.||..|.....|..||..||..:|:||.:||.|:|:|.
Zfish  2380 VAAKFQQSLLELIEKMERANPYFVRCIKPNQNKEPAVFDMELVSAQLCYSGILETVRIRREGYPI 2444

  Fly   801 RIPFQEFRQRYELLTPNVIPKGFMDGKKA----CEKMIQAL-ELDSNLYRVGQSKIFFRAGVLAH 860
            |:||..|..||:.|.      |......|    |..|::.| .:....::||.:|:|.:..:...
Zfish  2445 RMPFDVFLFRYKSLL------GLKQPPPANGENCVIMLRKLCPVRPGAFQVGVTKLFMKEEIYFL 2503

  Fly   861 LEEERD-------------------------FKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIR 900
            ||.:||                         |::.  |:..||.|||||.|:.|.|....|...|
Zfish  2504 LESKRDRVRHVAALTLQRYTRMFFVRKRYTAFRMK--IIRLQAHCRGFLTRKRYVKMRVSLVKFR 2566

  Fly   901 -----IIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQE 960
                 .:.|.  .|::||                    .|...:.|:|.:::..:|.
Zfish  2567 SLVHMYVDRK--RYIRLR--------------------YEARRKAEEEQRRIEMELS-------- 2601

  Fly   961 YERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQ 1001
               |.:...|....:..:|.|.::..|...|..|..:|..|
Zfish  2602 ---KREVVNVTHLVIPAELGALLQAAAGGRELHSDCLALVQ 2639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	79..122	CDD:460670	12/74 (16%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	268/724 (37%)
		Myosin_tail_1	931..2011	CDD:460256	13/71 (18%)
myo15aa	XP_073801013.1	None