Protein Alignment zip and Myo19

DIOPT Version :10

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: NP_001157208.1
• Gene: Myo19 / 497974
• RGDID: 1559961
• Length: 964
• Species: Rattus norvegicus
• Alignment Length: 983
• Identity: 282/983 - (28%)
• Similarity: 448/983 - (45%)
• Gaps: 184/983 - (18%)

  Fly   120 DDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLP-IYTEK 183
            ||:.|:||...:.|     |.||         :.||...:.||.:|...|.:||:|.:| :|..:
  Rat    38 DDLTKVNPVTLETV-----LRCL---------QARYTEDIFYTNAGCTLVALNPFKHIPQLYAPE 88

  Fly   184 IMERYKGIKRHEVP------PHVFAITDSAYRNM--LGDREDQSILCTGESGAGKTENTKKVIQF 240
            :|:.|     |..|      ||:|.:.:..|||:  |.:..:|||:.:||||||||..::.:::|
  Rat    89 LMQEY-----HAAPQPQKLKPHIFTVGEQTYRNVKSLIEPINQSIVVSGESGAGKTWTSRCLMKF 148

  Fly   241 LAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGEL 305
            .|.||||...                           .:|.          ||.|        .:
  Rat   149 YAVVAASPTS---------------------------CENH----------KMAE--------RI 168

  Fly   306 EQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDER 370
            |:::|.:||::||||||.|::|:|||||||||::..:.:..::||.::||||||:|...||..||
  Rat   169 EERILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQAASER 233

  Fly   371 TFHIFYQLLAGATPEQREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFN 435
            .||||||:..|||.|:|.::.|.:..::::|.|   |...:::.. |:.|.::|..:|:.:...|
  Rat   234 NFHIFYQICKGATKEERLQWCLPEGTAFSWLPN---PESSLEEDC-FEVTREAMLHLGIDTPTQN 294

  Fly   436 SIFRIVSAVLLFGSMKFRQERNNDQ-ATLPDNTVAQKIAHLLGLSVTD--MTRAFLTPRIKVGR- 496
            :||::::.:|..|::.|....:..| ..|.|.|........|.|.:.|  :..:.....||.|:
  Rat   295 NIFKVLAGLLHLGNVHFVDSEDEAQPCQLMDGTKGSVRTSALLLQLPDNMLLESMQIRTIKAGKQ 359

  Fly   497 -DFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELN 560
             ....|..::.:.:...:.:||..|.|:|.|||:.||.|:........:|||:||:.|||.|..|
  Rat   360 QQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADFSSWTAFIGLLDVYGFESFPDN 424

  Fly   561 SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLID-KPGGIMALLD 624
            |.|||||||.||||||.|.......:||||:.||:||.|::: .|.|..:||:: .|..|.:|::
  Rat   425 SLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNY-QDNQTCLDLLEGSPISICSLIN 488

  Fly   625 EECWFPKATD----KTFVDKLVSAHSM--HPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNM 683
            |||...:.:.    :|.::..::....  |.|..:.     ..|.::|:||.|.|..|..:.||.
  Rat   489 EECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSRE-----PSFVVMHFAGPVRYCTAGLVEKNK 548

  Fly   684 DPLNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLM 748
            ||:...:..|||.||||.::.::.      ...:..|..:...::|......||. :|..|.:|:
  Rat   549 DPVPPELTGLLQQSQDPLLMMLFP------ANPEEKTQEELSGQSRAPALTVVSK-FKASLEQLL 606

  Fly   749 DTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYEL 813
            ..|..|.|:::|||.||.:.:........||:||...|::|.|.|...|||.|:..|.|.:||:|
  Rat   607 QVLHKTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFMERYKL 671

  Fly   814 LT----------PNVIPKGFMDGKKACEK-----------------MIQALELDSN--------L 843
            ||          .::.|......:..|.|                 :||.....|:        |
  Rat   672 LTRLRPRTSSGLRSLCPAKGSSEQPLCAKEATLQPLLQDILHALPALIQTATTPSDPAKTAQIPL 736

  Fly   844 YRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAA 908
            | .|::|||....:|..||..|...:.......|...|    |...||:.:|..|..|||....:
  Rat   737 Y-CGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWR----RHRLQKQEKQRRAAVIIQAAFRS 796

  Fly   909 YLKLRN--------------WQWWRLYTKVKPLLEVTKQEEKLVQK-----EDELKQVREK---- 950
            :|..::              |..||:........|:...||||:.:     ...|.....:
  Rat   797 WLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKLMPQAPGTLRSSLSPAHTRFLGA 861

  Fly   951 ------LDTLAKNTQEYERKYQQALV-------------EKTTLAEQLQAEIELCAEAEESRSRL 996
                  |..:..|:.:..|.:|:.||             .|....:|.||.|.......:...:.
  Rat   862 IIHLWPLGLVLANSADGMRGFQRKLVAHACLRLPASGPSNKVQTPQQDQAGITSIRALPQGSIKF 926

  Fly   997 MARKQELE 1004
            ..||..|:
  Rat   927 HCRKSPLQ 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	79..122	CDD:460670	1/1 (100%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	235/764 (31%)
		Myosin_tail_1	931..2011	CDD:460256	19/102 (19%)
Myo19	NP_001157208.1	MYSc_Myo19	49..746	CDD:276846	239/778 (31%)
		IQCD	776..>801	CDD:467745	8/24 (33%)