Protein Alignment zip and didum

DIOPT Version :10

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: NP_724569.1
• Gene: didum / 35680
• FlyBaseID: FBgn0261397
• Length: 1800
• Species: Drosophila melanogaster
• Alignment Length: 2009
• Identity: 527/2009 - (26%)
• Similarity: 882/2009 - (43%)
• Gaps: 463/2009 - (23%)

  Fly    76 WTQKRLVWVPHENQGFVAASIKREH-------------GDEVEVELAETGKRVMILRDDIQKMNP 127
            :.|...:||||.:..:.:|:::..:             |...||:|...|..:..||      ||
  Fly     8 YAQGAKIWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLR------NP 66

  Fly   128 PKFDKVEDMAELTCLNEASVLHNIKDRYYS-GLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGI 191
            .......|:..|:.|:|..||||::.|:.. .:||||.|:..|.:|||.::|:|...|:..|:|.
  Fly    67 AILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGH 131

  Fly   192 KRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVP 256
            ...::.||:||:.:.||..:..:..:.||:.:||||||||.:.|..:::.|.|..|:
  Fly   132 AMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSE-------- 188

  Fly   257 HPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGN 321
                                                        .|.::|:::|.::||:|||||
  Fly   189 --------------------------------------------SETQVERKVLASSPIMEAFGN 209

  Fly   322 AKTVKNDNSSRFGKFIRINF-DASG--FISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGAT 383
            |||.:||||||||||.::.| :..|  |:.||.:.||||||||.:.||:.||.:||||||.|..:
  Fly   210 AKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHIFYQLCAARS 274

  Fly   384 --PEQREKFILDDVKSYAFLSNGSLP-VPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVL 445
              ||    .:||....:.||:.|..| :..|.|..:|..||::|.::|.:.:....|.:|::.:|
  Fly   275 KYPE----LVLDHQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIADIVKILAGIL 335

  Fly   446 LFG----SMKFR---QERNNDQATLPDNTVAQKI-AHLLGLSVTDMTRAFLTPRIKVGRDFVTKA 502
            ..|    |.||.   :|.::|...:..|.:..:| |.||.:|..|:.|..|..:|:...::|...
  Fly   336 HLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLMRKIESVNEYVLIP 400

  Fly   503 QTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCI 567
            .:.|..:.|.:|:||..|.::|:::|..:|:||:...:| .||||:||:.|||.||:|||||.||
  Fly   401 NSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQ-CSFIGVLDIYGFETFEVNSFEQFCI 464

  Fly   568 NYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKA 632
            ||.||||||.||..:|.||||||.:|||.|..||| .|.||.||||:...|::.||||||..||.
  Fly   465 NYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDF-YDNQPCIDLIESRLGVLDLLDEECRMPKG 528

  Fly   633 TDKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGS 697
            :|:::..||:...:..|.|.|..| |...|.|.|::..|:|....:|.||.|.:::.:..:|..|
  Fly   529 SDESWAGKLIGKCNKFPHFEKPRF-GTTSFFIKHFSDTVEYDVNGFLEKNRDTVSKELTQVLSES 592

  Fly   698 Q-------------DPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMF------RTVSHLYKEQ 743
            .             |...|:..|.:.:.|....:....|.|..||:.:.      :||...::|.
  Fly   593 NMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQES 657

  Fly   744 LAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFR 808
            ||.|:.||..|.|::||||.||.:|.|.|.:...::.|||..||||.:||...|||:|..:.:|.
  Fly   658 LASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFY 722

  Fly   809 QRYELLT-PNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEE--------- 863
            .||:||. .:.:.|.  |.|.:|..::.....|.:.||.|.::||||||.:|.||:
  Fly   723 MRYQLLVYRSKLDKN--DMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKY 785

  Fly   864 -------------ERDF-KISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRN 914
                         .|.| :|..:|...|...||:|||...|| :::..|..|:.:..      |.
  Fly   786 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQK-MREARAGLILSKYA------RG 843

  Fly   915 WQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQL 979
            |...|.|.:::..:...:...:.:...::...:|:....:     :.:|..:.||..:.  .::.
  Fly   844 WLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAV-----QIQRFVRGALARRA--YQKR 901

  Fly   980 QAEIELCAEAEESRSRLMARKQ------------ELEDMMQELETRIEEEEERVLALGGEKKKLE 1032
            :..|.:|..|..   |.:||::            .:|:....||.:|...::|:       .:|.
  Fly   902 RRNIIICQAAIR---RFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRI-------DELN 956

  Fly  1033 LNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQT 1097
            .:..:|:.:..|....:.||:|:|. |:|:.|..:   |...|:::.:....|.||
  Fly   957 RDNSNLKHKTSEISVLKMKLELKKT-LEAEFKNVK---AACQDKDKLIEALNKQLE--------- 1008

  Fly  1098 LAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKE--QLNERRVQ 1160
             ||.:||.:.|       |......||.:.:.|..|||::..:|:|: |:.|:.:  ::|:|. |
  Fly  1009 -AERDEKMQLL-------EENGHAQEEWISQKQTWRQENEELRRQID-EIIDMAKNAEVNQRN-Q 1063

  Fly  1161 VDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRR 1225
            .|.|.|::..|  ||.:...|..::...........:|..|:|......|.|.||:.|.::
  Fly  1064 EDRMLAEIDNR--ELNEAYQRAIKDKEVIENENFMLKEELSRLTAGSFSLHARKASNASSQ---- 1122

  Fly  1226 DLSEELEALKNELLDSLDTTAAQQELRSKREQELAT--------------LKKSLEEETVNHEGV 1276
                      ||  |.:...:|:..|...|..:|.:              |:..||||...|: |
  Fly  1123 ----------NE--DDVGYASAKNTLDINRPPDLLSKNYSYNDSTSLVVKLRSILEEEKQKHK-V 1174

  Fly  1277 LADM------RHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDR 1335
            |.:.      |||.:::...:::                  ||.||..|.:|...:.:|.:..
  Fly  1175 LQEQYIKLSSRHKPTEDSFRVSE------------------LEVENEKLRSEYDQLRTSIKHG-- 1219

  Fly  1336 RRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKS--ASNMES 1398
                         |::.|:....:.|||:..:.::|.    .||:...|:.|.:::|  ..:::.
  Fly  1220 -------------VEINELNAQHAALQEEVRRRREEC----IQLKAVLLQQSQSMRSLEPESLQM 1267

  Fly  1399 QLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKA 1463
            :..:..:|:|....|||    ..||:|||.:|:.|:          :..||.|:|   |||::
  Fly  1268 RGNDVNELMEAFHSQKL----INRQLESELKAITEE----------HNSKLVEMT---QEIER-- 1313

  Fly  1464 EEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDR-----LDKSKKK---IQSELEDATIELE 1520
                 |..|.:|.:|.:.:.|:..|....:.:.||||     |.|:..:   :|.||:.|..:|:
  Fly  1314 -----LNNEKDELQKVMFESIDEFEDSNVDTLRQNDRYLRRELQKAVAQFLLVQEELKLANAKLK 1373

  Fly  1521 AQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSV----SRELDEAFDK 1581
            |.|....:||.|       :.||...::......|......::|......:    |.:||:...:
  Fly  1374 AYRQDGGQLEHK-------IEEEMIRNKSNGTSADVGANVTKQKSQNPQGLMKFHSSDLDKILQR 1431

  Fly  1582 IEDLENKRKTLQNEL--------------DDLANTQGTADKNVHEL-----------EKAKRALE 1621
            :......| |:...|              .||.|    ||.:|.||           .:....:|
  Fly  1432 LLSALTPR-TVVGLLPGFPAYLIFMCIRYTDLTN----ADDDVRELLSKFVIQIKKMHRTPHPIE 1491

  Fly  1622 SQLAEL------------------------KAQNEELEDDLQLTEDAKLRLE--VNM-QALRSQF 1659
            :::..|                        :.||::...:..|.|..::.|:  ||: |||..|.
  Fly  1492 NRVIWLVNSITLLNLMKQYGDVDEYVKFNTEKQNQQQLKNFNLFEYRRVILDLIVNLYQALIMQI 1556

  Fly  1660 ERDLLAK---------------------------------EEGAEEKRRGLVKQLRDLETE---- 1687
            :..|..|                                 |.|.....:.|:.||.....:
  Fly  1557 QGLLDPKIVPAILNNDEIQRGRQAHGMRSRATSIGASSSPEHGGGPAWKQLIGQLEHFYKQFQHF 1621

  Fly  1688 -LDEERKQR---------TAAVASKKKLEGDLKEIETTMEMHNKVK--EDALKHAKKLQAQVKDA 1740
             ||....::         .|...:...|.||:...||.|.:...:.  ||.:: :||:...|..|
  Fly  1622 GLDNCYAEQIFHQLLYFICAVALNCLMLRGDICMWETGMIIRYNIGCIEDWVR-SKKMSNDVLTA 1685

  Fly  1741 LRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNAN 1805
            |....:   ..:.||  |:::|:.|:.    :..|...|::::..:.....:.|:...||.|
  Fly  1686 LAPLNQ---VSQLLQ--SRKSEQDVQT----ICDLCTSLSTAQVLKVMKSYKLDDYESEITN--- 1738

  Fly  1806 KGSLMIDEK--RRLEARIATLEEELEEEQSNS-EVLLDRS---------RKAQLQIEQL 1852
                :..||  .:|.||        :.::||| |..:|:.         |.:.:::|.:
  Fly  1739 ----VFLEKLTEKLNAR--------QMQKSNSDEFTIDQKFIQPFKVVFRYSDIKLEDI 1785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	79..122	CDD:460670	12/55 (22%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	265/743 (36%)
		Myosin_tail_1	931..2011	CDD:460256	218/1083 (20%)
didum	NP_724569.1	MYSc_Myo5	84..767	CDD:276831	265/743 (36%)
		IQ	900..922	CDD:197470	6/24 (25%)
		SMC_prok_B	<942..1365	CDD:274008	120/532 (23%)
		Myo5_CBD	1424..1792	CDD:271254	72/392 (18%)