|
Fly 55 PELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILR 119
|.|:....||.: |....:..|..|:|....:.||.|:::...|.:|..: .|.|..|.:..
Rat 15 PYLRKSEKERIE----AQNKPFDAKSSVFVVDAKESFVKATVQSREGGKVTAK-TEGGATVTVKD 74
Fly 120 DDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKI 184
|.:..|||||:||:||||.:|.|:|.:||:|:|:||.:.:||||||||||.|||||.||:|..::
Rat 75 DQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEV 139
Fly 185 MERYKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKP 249
:..|:|.||.|.|||:|:|:|:||:.||.|||:||||.|||||||||.|||:|||:.|
Rat 140 VAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFA------- 197
Fly 250 KGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANP 314
||.|....|..|..|...:|.||.|::.|||
Rat 198 ----------------------------------TIAVTGEKKKEEAPSGKMQGTLEDQIISANP 228
Fly 315 ILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLL 379
:||||||||||:|||||||||||||:|..:|.::.|:||||||||||...|.|.||::|||||::
Rat 229 LLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIM 293
Fly 380 AGATPEQREKFIL-DDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSA 443
:...|:..|..:: .:...|||:|.|.:.||.:||..|..||..:::|:|.||::..||:::..|
Rat 294 SNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGA 358
Fly 444 VLLFGSMKFRQERNNDQATLPDNT-VAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQ 507
|:.:|:|||:|::..:||. ||.| ||.|.|:|..|:..|:.:|...||:|||.::|||.||.:|
Rat 359 VMHYGNMKFKQKQREEQAE-PDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQ 422
Fly 508 VEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNE 572
|..||.|:|||.||:||.|:|.|||:.|| ||:....|||:||:||||||:.||.||||||:|||
Rat 423 VYNAVGALAKAVYEKMFLWMVTRINQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNE 486
Fly 573 KLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTF 637
||||.|||.||:||||||::|||||:|||||:||...|:||:||.||.::|:|||.||||||.:|
Rat 487 KLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSF 551
Fly 638 VDKLVSAH------SMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQG 696
.:||...| ...||..|.... |.|::|||||.|||:.|.||.||.|||||.:|.|.|.
Rat 552 KNKLYEQHLGKSNNFQKPKPAKGKVE--AHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQK 614
Fly 697 SQDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRC 761
|....:..::..|.....|:......:.||:.:...|:|||.|::|.|.|||..||:|:|:||||
Rat 615 SSMKTLAYLFSGAAAAAEAESGGGGGKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 679
Fly 762 IIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKG-FMD 825
||||..|..|.::..|||.|||||||||||||||:|||:||.:.:|:|||::|..:.||:| |:|
Rat 680 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 744
Fly 826 GKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQ 890
.|||.||::.::::|...|:.|.:|:||:||:|..|||.||.|::.||...||.|||:|||..||
Rat 745 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLARVEYQ 809
Fly 891 KRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLA 955
|.:::..:|..||.|..|::.:::|.|.:||.|:||||:..:.|:::...::|.::.:|.|....
Rat 810 KMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKENLAKAE 874
Fly 956 KNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEER 1020
...:|.|.|....:.||..|..|:|:|.:..|:|||...:|:..|.:||..::|:..|.|:|||.
Rat 875 AKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 939
Fly 1021 VLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKK 1085
...|..:|:|||....:|::.:::.|....|::.||...:.|:|...|::|..|:...||.||||
Rat 940 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKK 1004
Fly 1086 LLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADL 1150
.|:|........|..||:|...|.|.|.|.|..:.:||..|.::::.|.:.:|:|||:| .||
Rat 1005 ALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLE---GDL 1066
Fly 1151 K-EQLNERRVQVDEMQ--AQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEA 1212
| .|.:...|:.|:.| .:|.|:|.|::....:|::|.|.....||..:||::::.|::|::||
Rat 1067 KLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1131
Fly 1213 EKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVL 1277
|:|:||||||.|.|||.|||.:...|.::...|:||.|:..|||.|...:::.|||.|:.||...
Rat 1132 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1196
Fly 1278 ADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAES 1342
|.:|.||:..:..:.:|::||::.|..|||.|..::.|..|||:.:..::.|:...::..:..|.
Rat 1197 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLED 1261
Fly 1343 QIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLL 1407
|::||:.|..|.:|..:||..:..:||.|:...:.||:|.:...|...:.......|:.|.::.|
Rat 1262 QVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQL 1326
Fly 1408 EEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDA-DLAK 1471
|||.:.|..|:..|:....:.:.|:||.||:.|||...:|.:::..:::.:.:.|.|.|| ...:
Rat 1327 EEEVKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTE 1391
Fly 1472 ELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNF 1536
||||.||:|.:.::..|..|:.:.|:...|:|:|:::|:|:||..|::|........|:|||:||
Rat 1392 ELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNF 1456
Fly 1537 DKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLAN 1601
||||||.|...|:...|.:.:::|:|...|::..:....:|:.|::|.|:.:.|.||.|:.||..
Rat 1457 DKILAEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1521
Fly 1602 TQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAK 1666
......|.:|||||.|:.:|.:.:||:|..||.|..|:..|...||:::.:..::|:.:|.:..|
Rat 1522 QIAEGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEK 1586
Fly 1667 EEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAK 1731
:|..::.:|..::.:..:::.||.|.:.|..|:..|||:||||.|:|..:...|::..:||::.:
Rat 1587 DEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNRMAAEALRNYR 1651
Fly 1732 KLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDEL 1796
..|..:||.....::|...:|:|:......||:...|:||:.:|...|..:||:|:.||.|..:.
Rat 1652 NTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1716
Fly 1797 AEEIANNANKGSLMIDEKRRLEARIATLEEELE---EEQSNSEVLLDRSRKAQLQIEQLTTELAN 1858
:|.:.....:.:.:|:.|::||..|:.::.|:| :|..|:| ::::||......:..||..
Rat 1717 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAE---EKAKKAITDAAMMAEELKK 1778
Fly 1859 EKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQ 1923
|:..|...|..:..||:..|:|:.:|.|.|.......|..|..|||::..||.::|||.|..:..
Rat 1779 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEA 1843
Fly 1924 QKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQR 1988
.|..||.::::||||...|::|::|.:.::.:|||.|::|..||..:|.||:......:.||.|.
Rat 1844 IKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKIQH 1908
Fly 1989 ECEDMIESQEAMNREINSLKTKLR 2012
|.|:..|..:....::|.|:.|.|
Rat 1909 ELEEAEERADIAESQVNKLRVKSR 1932
| 
