Protein Alignment zip and Myo1f

DIOPT Version :10

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: NP_444444.2
• Gene: Myo1f / 17916
• MGIID: 107711
• Length: 1098
• Species: Mus musculus
• Alignment Length: 995
• Identity: 296/995 - (29%)
• Similarity: 485/995 - (48%)
• Gaps: 194/995 - (19%)

  Fly   133 VEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVP 197
            |:||..|..:.|.:::.|::.|:....|:||.|...:.|||:|::|.:|::.::.|:|..::|.|
Mouse    19 VDDMVLLPQITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENP 83

  Fly   198 PHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLI 262
            ||::|:||:.|||||.|.|:|.::.:||||||||...|.::.:::.|:.    |...|.|
Mouse    84 PHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSG----GGDKVQH----- 139

  Fly   263 NFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKN 327
                                                      ::..:||:||:||||||||||:|
Mouse   140 ------------------------------------------VKDIILQSNPLLEAFGNAKTVRN 162

  Fly   328 DNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFIL 392
            :|||||||:..|.|...|...|..|..:||||||.:.|.::||.|||:||||.||:.||::...|
Mouse   163 NNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGL 227

  Fly   393 DDVKSYAFLS-NGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQER 456
            .....|.:|: :.:..|.|.||.::|..|:.:|.::|:.:.....:.::|:.:|..|::.|.:|.
Mouse   228 MTPDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVIGIPTSVQQLVLQLVAGILHLGNISFCEEG 292

  Fly   457 NN------DQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKV-----GR-DFVTKAQTKEQVE 509
            |.      |....|        |:|||:. :...:..||.| |:     || :.:......||..
Mouse   293 NYARVESVDLLAFP--------AYLLGID-SGRLQEKLTSR-KMDSKWGGRSESIDVTLNVEQAA 347

  Fly   510 FAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKL 574
            :..:|:||..|.|:|.:||..|||::.:.:.:.:  ||:||:.|||||:.|.|||.|||:.||||
Mouse   348 YTRDALAKGLYARLFDFLVEAINRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKL 410

  Fly   575 QQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLID---KPGGIMALLDEECWFPKAT--- 633
            ||:|.......|||||.:|||.|..|:: .:.:...|||:   .|.|||::||:.|....||
Mouse   411 QQIFIELTLKAEQEEYVQEGIRWTPIEY-FNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGG 474

  Fly   634 -DKTFVDKLVSAHSMHPKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGS 697
             |:|.:.||.:|...|..|....    |.|.|.||||:|.|..:.:..:|.|.|..:::.|:|.|
Mouse   475 ADQTLLQKLQAAVGTHEHFNSWS----AGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSS 535

  Fly   698 QDPFVVNIWKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCI 762
            ...|:..::.:...:               .:||...|.....|:|...|:.||:...|:::|||
Mouse   536 DQDFLRMLFPEKLNI---------------DKKGRPSTAGSKIKKQANDLVSTLKKCTPHYIRCI 585

  Fly   763 IPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGK 827
            .||..||....:...|..|:...|:.|.||:.|.||..|..|.:|.|||.:|||...|:...|.:
Mouse   586 KPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPRWRGDER 650

  Fly   828 KACEKMIQALELDSNLYRVGQSKIFFR-AGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQK 891
            :..:.:::|:.::.:.|::|.:|:|.: ...|..|||.|:.|........|...|..:|.|.|::
Mouse   651 QGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAVRKYEE 715

  Fly   892 RLQQLNAIRI---------IQRNCAA-YLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQ 946
            ..::.:.|.:         |.||... ||.|                          ::..||:|
Mouse   716 MREEASNILLNKKERRRNSINRNFVGDYLGL--------------------------EERPELRQ 754

  Fly   947 V---REKLDTLAKNTQEYERKY---QQALV------------------EKTTLAEQLQAEIELCA 987
            .   ||::| .|.:..:|:|::   ::.|:                  ||..:.|.|:.::::
Mouse   755 FLAKRERVD-FADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKRGPEKGLVREVLKKKLDI-- 816

  Fly   988 EAEESRSRLMARKQELEDMMQE------LETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEE 1046
              :..|...::.:|:...::||      ||:..:.|...:|.     |:.             ||
Mouse   817 --QALRGVSLSTRQDDFFILQEEAADSFLESIFKTEFVSLLC-----KRF-------------EE 861

  Fly  1047 AARQKLQLE-KVQLDAKIKK 1065
            |||:.|.|. ...|..::||
Mouse   862 AARRPLPLTFSDLLQFRVKK 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	79..122	CDD:460670
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	240/728 (33%)
		Myosin_tail_1	931..2011	CDD:460256	33/166 (20%)
Myo1f	NP_444444.2	MYSc_Myo1	31..677	CDD:276829	240/728 (33%)
		Myosin_TH1	717..915	CDD:461801	40/214 (19%)
		PHA03247	<920..1043	CDD:223021
		SH3_MyoIe_If_like	1045..1097	CDD:212761