Protein Alignment zip and myh9

DIOPT Version :9

• Sequence 1: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0265434
• Length: 2056
• Species: Drosophila melanogaster
• Sequence 2: XP_017949131.2
• Gene: myh9 / 100487997
• XenbaseID: XB-GENE-1002222
• Length: 1960
• Species: Xenopus tropicalis
• Alignment Length: 2008
• Identity: 1184/2008 - (58%)
• Similarity: 1538/2008 - (76%)
• Gaps: 69/2008 - (3%)

  Fly    58 KYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDI 122
            |||.|:||..|:|..||:|..|:|||||.|..||.|||:|.|.|||..|||||.||:..:.:|||
 Frog     8 KYLYVDRNFVNNPLAQADWAAKKLVWVPSEKHGFEAASVKEEVGDEAIVELAENGKKAKVNKDDI 72

  Fly   123 QKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMER 187
            ||||||||.|||||:||.||||||||||:|:|||||||||||||||||:||||.||||:|:|:|.
 Frog    73 QKMNPPKFSKVEDMSELACLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKYLPIYSEEIVEM 137

  Fly   188 YKGIKRHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGS 252
            |||.||||:|||::||||:|||:|:.||||||||||||||||||||||||||:|||||.|.
 Frog   138 YKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVATSH---- 198

  Fly   253 GAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILE 317
                                                        .|..::||||:||||||||||
 Frog   199 --------------------------------------------KSKKEQGELERQLLQANPILE 219

  Fly   318 AFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGA 382
            |||||||||||||||||||||||||.:|:|.|||||||||||||||||||:||||||||.||:||
 Frog   220 AFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGA 284

  Fly   383 TPEQREKFILDDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLF 447
            ....:...:|:....|.|||||.:.:||..|...||.|:::|.|||.|.|:...:.|:||:||..
 Frog   285 GEHLKSDLLLEAYNKYRFLSNGHVTIPGQQDKDLFQETMEAMKIMGFTEEEQIGLLRVVSSVLQL 349

  Fly   448 GSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAV 512
            |::.|::|||.|||::||||.|||:.||:|::|.|.||..|.||||||||||.|||||||.:||:
 Frog   350 GNIAFKKERNTDQASMPDNTAAQKLCHLMGINVNDFTRGILLPRIKVGRDFVQKAQTKEQADFAI 414

  Fly   513 EAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQL 577
            ||:|||.|||||:|||.|:|::||:|||||||||||||:||||||||||||||||||||||||||
 Frog   415 EALAKATYERMFRWLVMRVNKALDKTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQL 479

  Fly   578 FNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG---GIMALLDEECWFPKATDKTFVD 639
            ||||||||||||||||||||.||||||||||.|:||:||.   ||:|||||||||||||||:||:
 Frog   480 FNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIEKPAGPPGILALLDEECWFPKATDKSFVE 544

  Fly   640 KLVSAHSMHPKFMK-TDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVV 703
            |:|.....|.||.| ...:..|||.|:||||:|||.|.:||:|||||||:|:.:||..|.|.||.
 Frog   545 KVVQEQGSHSKFQKPKQLKDKADFCIIHYAGKVDYKADEWLLKNMDPLNDNVATLLNQSSDKFVS 609

  Fly   704 NIWKDAE-IVGMAQQA-LTDTQF-GA-RTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIP 764
            .:|:|.: |||:.|.| :.||.. || :|||||||||..||||||:|||.|||||||||||||||
 Frog   610 ELWRDVDRIVGLDQVAGMADTALPGAFKTRKGMFRTVGQLYKEQLSKLMATLRNTNPNFVRCIIP 674

  Fly   765 NHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMDGKKA 829
            ||||::||:||.|||||||||||||||||||||||||:.|||||||||:||||.|||||||||:|
 Frog   675 NHEKKSGKLDAHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQA 739

  Fly   830 CEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQ 894
            |..||:||||||||||:||||:|||||||||||||||.||:|:|::|||||||:|||:.:.||.|
 Frog   740 CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIISFQAFCRGYLARKAFAKRQQ 804

  Fly   895 QLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQ 959
            ||.|:::|||||||||||||||||||:|||||||:..:.:|:|..||.||::|:|...:..:...
 Frog   805 QLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQANRFDEELHAKEVELQKVKELQVSSEQKVS 869

  Fly   960 EYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLAL 1024
            |.|........||..|.|||||||||||||||.|:||..:|||||:::.:||:|:||||||...|
 Frog   870 EMENVQMMLQQEKMQLQEQLQAEIELCAEAEEMRARLATKKQELEEILHDLESRVEEEEERCQIL 934

  Fly  1025 GGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEE 1089
            ..:|||::.||.:||||||||||||||||||||.::||:||.|||:.:.:|||.||.|||||.||
 Frog   935 QADKKKMQHNIVELEEQLEEEEAARQKLQLEKVTVEAKMKKLEEDVLVLEDQNSKLGKEKKLYEE 999

  Fly  1090 RANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQL 1154
            |..:.:..|||||||:|.|||||.|||..||:|||||.::::||||.::::||:|.:..||.:|:
 Frog  1000 RIAEFTTNLAEEEEKSKSLAKLKNKHETMISDLEERLRREEKQRQELEKTRRKLEGDSTDLHDQI 1064

  Fly  1155 NERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAK 1219
            .|.:.|:.|::.||||:||||...|.|::||||.|..|.|..||||||::|:|||||.|:|||.|
 Frog  1065 AELQAQIAELKMQLAKKEEELQAALARVEEESAQKNIALKKIRELESQISELQEDLETERAARNK 1129

  Fly  1220 AEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKH 1284
            |||.:|||.|||||||.||.|:||:||||||||:|||||:..|||:||:|...||..:.::|.||
 Frog  1130 AEKQKRDLGEELEALKTELEDTLDSTAAQQELRTKREQEVTQLKKTLEDEARTHEVQIQEIRQKH 1194

  Fly  1285 SQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQV 1349
            ||.:..:::|||..::.|..|||||.:||.|..:||.|::::...:.:::.:||:.|.|:.||||
 Frog  1195 SQAVEELSEQLEQTKRLKGNLEKAKQSLEGERNELANEVKALLQGKGDSEHKRKKVEGQLQELQV 1259

  Fly  1350 KLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQK 1414
            |:.|.:|.|:||.||..:||.|.:|:.:.|.:|:.|:....|..|.:||||.:.|:||:||||||
 Frog  1260 KVTEGDRVRAELSEKANRLQVELDNVNSLLSQADGKSIKLGKDFSTLESQLQDTQELLQEETRQK 1324

  Fly  1415 LGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKR 1479
            |..|:||:|:|.||..|.||:||::|||:|..::::.:.:||.::|||.:|:....:.:||.||:
 Frog  1325 LSFSTKLKQMEDEKNGLLEQIEEEEEAKKNLSKQISTLQSQMADMKKKMDENVGSLETVEELKKK 1389

  Fly  1480 LNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEK 1544
            |.||:|::.::.:|..|..|:|:|:|.::|.||:|..::|:.||..|..||||||.||::|.|||
 Frog  1390 LQKDLESVNQRFEEKAAAYDKLEKTKTRLQQELDDIAVDLDHQRQIVSNLEKKQKKFDQLLGEEK 1454

  Fly  1545 AISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKN 1609
            .||.:.|.|||.||.||||||||.|:::|.|:||.:...:||...|.|:.|::||.:::....|:
 Frog  1455 TISAKYADERDRAEAEAREKETKALALARSLEEALEAKAELERLNKQLRTEMEDLVSSKDDVGKS 1519

  Fly  1610 VHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKR 1674
            ||||||:|||||.|:.|:|.|.|||||:||.|||||||||||:||:::||||||..::|.:|:|:
 Frog  1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEDKK 1584

  Fly  1675 RGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKD 1739
            :.||:|::::|.||::|||||:.|||::||||.|||::|..::..||.:|:|:|..:|||||:||
 Frog  1585 KQLVRQVKEMEAELEDERKQRSVAVAARKKLEMDLKDLEGQIDSANKNREEAIKQLRKLQAQIKD 1649

  Fly  1740 ALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNA 1804
            ..|:.::.:|:::::.:.|||:|:|:|::|||::.:.|:||::||.:|.|:.||||||:|||||:
 Frog  1650 YQRELDDTRASRDDILSQSKESEKKLKSMEAEMIHMQEELAAAERGKRQAQQERDELADEIANNS 1714

  Fly  1805 NKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENG 1869
            .||:|.::||||||:|||.|||||||||.|:|::.||.:||.||::||..:|..|:||:|||||.
 Frog  1715 GKGALALEEKRRLESRIAQLEEELEEEQGNTELVNDRLKKATLQVDQLNADLNAERSNAQKNENA 1779

  Fly  1870 RALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKI 1934
            |..::|||||||.||.|:|...::|.||.|..||||||.|||||:.|.|||....|..|:.:||:
 Frog  1780 RQQMDRQNKELKTKLQELEGTVKSKFKANITALEAKIAQLEEQLDTETKERQNASKQVRRTEKKL 1844

  Fly  1935 KELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEA 1999
            |::.|.::||||:.:|:|:|.:|.|.|:|.|||.::|.|||.|:....:||.|||.||..|:.||
 Frog  1845 KDVMMQVDDERRNAEQYKDQAEKNNVRMKQLKRQVEEAEEEAQRANAMRRKLQRELEDATETAEA 1909

  Fly  2000 MNREINSLKTKLRRTGGIGLSSSRLTGTPSSKRAGGGGGGDDSSVQDESLDGE-DSAN 2056
            ||||:|:||:||||.|.:...:.|:          |..|.|::|  ||.|||: ||.:
 Frog  1910 MNREVNTLKSKLRRGGDVPFVTRRI----------GRKGVDEAS--DEDLDGKADSGD 1955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zip	NP_523860.2	Myosin_N	80..117	CDD:280832	23/36 (64%)
		Myosin_head	133..854	CDD:278492	496/728 (68%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	486/716 (68%)
		Myosin_tail_1	931..2011	CDD:279860	564/1079 (52%)
		Prefoldin	1431..1515	CDD:298833	32/83 (39%)
		FAM76	<1847..1926	CDD:292665	44/78 (56%)
myh9	XP_017949131.2	Myosin_N	29..68	CDD:397036	24/38 (63%)
		Motor_domain	95..764	CDD:419868	486/716 (68%)
		Myosin_tail_1	842..1921	CDD:396244	564/1078 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1149	1.000	Domainoid score	I16
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	2376	1.000	Inparanoid score	I34
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D40305at33208
OrthoFinder	1	1.000	-	-		FOG0000014
OrthoInspector	1	1.000	-	-		otm49537
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R786
SonicParanoid	1	1.000	-	-		X58
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.090