Protein Alignment CG3829 and SCARB2

DIOPT Version :9

• Sequence 1: NP_001286874.1
• Gene: CG3829 / 38000
• FlyBaseID: FBgn0035091
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 139/473 - (29%)
• Similarity: 230/473 - (48%)
• Gaps: 40/473 - (8%)

  Fly    82 GTLIMLGVMFLLFVISVTGFFVMWFTEYYNNTILENLILAENSDTANSWLNPD-PKYDTLLKAHI 145
            |||.:     ||.|.|||......|.:..:.:|.:.::|...::..:||..|. |.|   .:.:.
Human    10 GTLSL-----LLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVY---TQFYF 66

  Fly   146 FHYPNIDDYLAGRADKIKVVDVGPLTYQEHTVKDEVSFNKN-FTVSFRDRKSYKFLPEKSSIGEH 209
            |:..|.::.|.|...:::  :|||.||:|...|..:.|..| .|:|....|:|.| ....|:|:.
Human    67 FNVTNPEEILRGETPRVE--EVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVF-ERDQSVGDP 128

  Fly   210 EV--VRVPNVPLISAAGPVKRMKA-FERLAVSTWIKQFKEPLFKNLTVSEYLWGYEDSIIKLKSL 271
            ::  :|..|:|:::.   ::..:. |.|..:...:|.:::.||...||.|.||||:|.|:.|..:
Human   129 KIDLIRTLNIPVLTV---IEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHV 190

  Fly   272 GRG--RRRFGLLMSRNGTSVDSVQLNTGEDDITKFSIITQFNGMPQLDYWEGDECNRIDGSEPSM 334
            .|.  ...|||...:|||:.......||||....|:.|.::||...||:|..|:||.|:|::...
Human   191 FRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDS 255

  Fly   335 FSPHLLQDRSTVNVFLQVLCRKVPLHFEKEVTIYNDIDVLRYRTPMDVFSHPSKNPANQCYCQNT 399
            |.|.:.:| ..:.||....||.|.:.|....:: ..:...||:.|.::.::.|.|..   :|...
Human   256 FHPLITKD-EVLYVFPSDFCRSVYITFSDYESV-QGLPAFRYKVPAEILANTSDNAG---FCIPE 315

  Fly   400 ELCLPSGVINATKCYGDAPIFPSFPHFFTGDPVLYQDFEGIEPDAAVHQTYADIHPRFGFPISGA 464
            ..||.|||:|.:.|...|||..|||||:..|.......||:.|:...|:|:.||:|..|..:..|
Human   316 GNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAA 380

  Fly   465 SRVQINIMLDKTPILRNQGDRLKNTTILPLMWIEITSGDFSEEVLHTLYLSTFGLNAIQQTLKYG 529
            .|.||||.:.|.......||  ..|.:.|:|::        .|.:|....:...|.::..|
Human   381 KRFQINIYVKKLDDFVETGD--IRTMVFPVMYL--------NESVHIDKETASRLKSMINT---- 431

  Fly   530 TLLISVTSFSLIVAGVYY 547
            ||:|:...:.::..||::
Human   432 TLIITNIPYIIMALGVFF 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3829	NP_001286874.1	CD36	91..546	CDD:279474	135/461 (29%)
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	130/450 (29%)
		Important for interaction with GBA	155..191		13/35 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.930