DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3829 and scarb2c

DIOPT Version :9

Sequence 1:	NP_001286874.1	Gene:	CG3829 / 38000	FlyBaseID:	FBgn0035091	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001352071.1	Gene:	scarb2c / 337532	ZFINID:	ZDB-GENE-030131-5789	Length:	478	Species:	Danio rerio

Alignment Length:	459	Identity:	147/459 - (32%)
Similarity:	232/459 - (50%)	Gaps:	20/459 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 NNTILENLILAENSDTANSWLNPDPKYDTLLKAHIFHYPNIDDYLAGRADKIKVVDVGPLTYQEH 175
            |||:.:.::|...::..:.|.||.|  ...::.:.|:..|..:.::|  ||..||.:||.||:|:
Zfish    36 NNTVKQQIVLENGTEAFSVWQNPPP--PVYMQFYFFNLTNPAEVMSG--DKPSVVQIGPYTYREY 96

  Fly   176 TVKDEVSFNKNFT-VSFRDRKSYKFLPEKSSIGEHEVVRVPNVPLISAAGPVKRMKAFERLAVST 239
            ...:||.|..|.| |:..:.|:|.|.|..|...:.::||..|:|.::.....|. ....|| :|.
Zfish    97 RPMEEVKFMDNGTRVAAINPKTYVFEPNMSRGSQDDLVRTVNIPAVTVMEKYKD-SILARL-ISD 159

  Fly   240 WIKQFKEPLFKNLTVSEYLWGYEDSIIKLKSLGRGRRRFGLLMSRNGTSVDSVQLNTGEDDITKF 304
            .:|.....:|:...|.:.||||||.::|...:......|||...:|||..||..|.||:.|...|
Zfish   160 LMKAKGVGVFETFRVGDLLWGYEDPLLKELHMLVPDDHFGLFYKKNGTEYDSYVLLTGKPDYQDF 224

  Fly   305 SIITQFNGMPQLDYWEGDECNRIDGSEPSMFSPHLLQDRSTVNVFLQVLCRKVPLHFEKEVTIYN 369
            :.|.::||...|::|..:|||.|:|::.:.|.| ::.....:.:|...|||.:.:.:|.:|:: .
Zfish   225 ASIDEWNGQRSLNWWSSEECNMINGTDGASFHP-IITKADRLYIFSSDLCRSLYVQYECDVSV-Q 287

  Fly   370 DIDVLRYRTPMDVFSHPSKNPANQCYCQNTELCLPSGVINATKCYGDAPIFPSFPHFFTGDPVLY 434
            .:...|:..|.||||.|..||.|..:|.....||.||::||:.|...|||..|.|||:..|....
Zfish   288 GVPGFRFVPPADVFSSPDINPDNAGFCVPPGHCLGSGLLNASVCKQGAPIIMSSPHFYQADQKFV 352

  Fly   435 QDFEGIEPDAAVHQTYADIHPRFGFPISGASRVQINIMLDKTPILRNQGDRLKNTTILPLMWIEI 499
            .|..|::|....|||:|||:|..|..:.||.|||:|:.|.:.......|.  ..|.:.|:|:|.
Zfish   353 DDIWGMKPIKEEHQTFADINPLTGIVLQGAKRVQVNVYLQQHSSFSQTGK--IQTLVFPVMYIN- 414

  Fly   500 TSGDFSEEVLHTLYLSTFGLNAIQQTLKYGTLLISVTSFSLIVAGVYYLNSRREQQLQESKTSAE 564
            .|....||....|:......|.:   :....::|||.    |:.|:.::.....||:..| |.||
Zfish   415 ESAFIDEESAKKLHAVVLNANVV---INIPFIVISVG----ILLGIIFIVLMCRQQMPPS-TLAE 471

  Fly   565 LEAL 568
            .|.|
Zfish   472 REPL 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3829	NP_001286874.1	CD36	91..546	CDD:279474	139/435 (32%)
scarb2c	NP_001352071.1	CD36	15..457	CDD:307331	139/438 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920