DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3829 and scarb2a

DIOPT Version :9

Sequence 1:	NP_001286874.1	Gene:	CG3829 / 38000	FlyBaseID:	FBgn0035091	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_775366.1	Gene:	scarb2a / 192340	ZFINID:	ZDB-GENE-020419-29	Length:	531	Species:	Danio rerio

Alignment Length:	493	Identity:	151/493 - (30%)
Similarity:	247/493 - (50%)	Gaps:	32/493 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 LIMLGVMFLLFVISVTGFFVMWFTEYYNNTILENLILAENSDTANSWLNPDPKYDTLLKAHIFHY 148
            |::||:..||..:         |.......|.:.:.|||||...:.|:||.|  ...::...|:.
Zfish    18 LLILGIALLLAQV---------FQTMIQERIKKEITLAENSRVLDGWINPPP--PVYMQYFFFNV 71

  Fly   149 PNIDDYLAGRADKIKVVDVGPLTYQEHTVKDEVSFNKNFTVSF-RDRKSYKFLPEKSSIGEHEVV 212
            .|.|::|||: :|.||..:||.||:|:..::.|::.:|.|..| .:.||:.|| ...|.|:.||.
Zfish    72 TNPDEFLAGK-EKAKVTQMGPYTYREYRPRENVTYLENGTKIFATNPKSFVFL-RNMSAGDPEVD 134

  Fly   213 RVP--NVPLISAAGPVKRMKAFERLAVSTWIKQFKEPLFKNLTVSEYLWGYEDSII-KLKSL-GR 273
            ||.  |:|:|:....:.....|.|.|||.::......||.|.||.|.|||::|.:: ||.:: ..
Zfish   135 RVTTVNIPMIAVMNELNSYSFFVRTAVSMYMGSMGMGLFMNRTVHEILWGFKDPLLTKLHAMRPE 199

  Fly   274 GRRRFGLLMSRNGTSVDSVQLNTGEDDITKFSIITQFNGMPQLDYWEGDECNRIDGSEPSMFSPH 338
            ....|||:.::|||.......:|||.:...:..|..:||:.|:::|..::.|.|:|::.|:|..
Zfish   200 VDEHFGLMYNKNGTHEGEFVFHTGEKNYMNYGKIDTWNGISQMNWWSSNQSNMINGTDGSVFHT- 263

  Fly   339 LLQDRSTVNVFLQVLCRKVPLHFEKEVTIYNDIDVLRYRTPMDVFSHPSKNPANQCYCQNTELCL 403
            .|..:..:.:|...|||.:.|.:.:::.: ..|...|:..|.||.:.|.:||||..:|.....||
Zfish   264 FLSRKELLYIFAADLCRSIHLGYVRDMEV-KGIPAFRFAPPSDVLAPPDENPANAGFCVPAGDCL 327

  Fly   404 PSGVINATKCYGDAPIFPSFPHFFTGDPVLYQDFEGIEPDAAVHQTYADIHPRFGFPISGASRVQ 468
            ..||:..:.|...|||..|||||:..|.......||:.|:...|:||.||:|..|.||....|.|
Zfish   328 GKGVLKVSVCRQGAPIVVSFPHFYQADERYINAIEGMNPNEEEHETYLDINPTTGVPIRACKRAQ 392

  Fly   469 INIMLDKTPILRNQGDRLKNTTILPLMWIEITS--GDFSEEVLHTLYLSTFGLNAIQQTLKYGTL 531
            :||:|.:.....|  .:..|.||.|:|::..|:  .|.|...:..|.|      .:.....:..:
Zfish   393 LNIILKRVRGFPN--TKFLNETIFPIMYVNETATIDDESAAQMRMLLL------IVTVVSNFPVI 449

  Fly   532 LISVTSFSLIVAGVYYLNSRREQQLQESKTSAELEALN 569
            ::::....|:|  :.:|..|..|:..|.|.....||.:
Zfish   450 ILALGVILLVV--LIFLVCRNRQRKNEVKRIDFTEAFH 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3829	NP_001286874.1	CD36	91..546	CDD:279474	141/461 (31%)
scarb2a	NP_775366.1	CD36	30..463	CDD:279474	139/457 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030