Protein Alignment KIF5C and kif5c

DIOPT Version :10

• Sequence 1: NP_004513.1
• Gene: KIF5C / 3800
• HGNCID: 6325
• Length: 957
• Species: Homo sapiens
• Sequence 2: NP_001116747.1
• Gene: kif5c / 565563
• ZFINID: ZDB-GENE-081105-14
• Length: 985
• Species: Danio rerio
• Alignment Length: 957
• Identity: 757/957 - (79%)
• Similarity: 857/957 - (89%)
• Gaps: 8/957 - (0%)

Human     1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQEQVYNA 65
            |.|.|||.:|||||||||||:||.||||:||||||::||||. ||||:|||||||||||||||:.
Zfish     1 MVDAAECCVKVMCRFRPLNESEINRGDKYIPKFKGEDTVVIA-GKPYIFDRVLPPNTTQEQVYDT 64

Human    66 CAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFH 130
            ||||||||||:||||||||||||||||||||||:||:.||||||||||.|||:||||||||||||
Zfish    65 CAKQIVKDVLDGYNGTIFAYGQTSSGKTHTMEGQLHNAQLMGIIPRIAQDIFEHIYSMDENLEFH 129

Human   131 IKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAV 195
            ||||||||||||||||||||||||||||||||||:|||||||||||||:||||||||||||||||
Zfish   130 IKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPFVKGCTERFVSSPEDVMDVIDEGKANRHVAV 194

Human   196 TNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||
Zfish   195 TNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGSVLDEAKNINKSLS 259

Human   261 ALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAK 325
            ||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||
Zfish   260 ALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVYNEAETKSTLMFGQRAK 324

Human   326 TIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNL 390
            |||||||||:|||||||||||||||||.:.||.:||.||.||.|||.||.||.:||.|.|:.||
Zfish   325 TIKNTVSVNMELTAEEWKKKYEKEKEKTRNLKIIIQRLENELKRWRKGETVPVNEQHSNKESKN- 388

Human   391 EPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDEL 455
              |:..|:||..||....:|..||.:|:|.|:.||:|||||||||||.|||||.|||||:|||||
Zfish   389 --CEAAPVIDTSAPPPEPLSDAEKTQYEELINDLYQQLDDKDDEINQHSQLAEDLKQQMVDQDEL 451

Human   456 LASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELA 520
            |||||||||||||:|.|||.|||.||:||||||||||||||||||||.|||:|::.|.||:|||.
Zfish   452 LASTRRDYEKIQEDLNRLQRENETAKEEVKEVLQALEELAVNYDQKSHEVEEKSKTNNQLSDELV 516

Human   521 QKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFT 585
            ||::.|...:|:||.|:|||.|.::|:.|||:|||:||.|||.:|..||.| |:::||.:|||||
Zfish   517 QKSSALAGVERDLSSLKELSEHHRRRSAEILSLLLRDLCEIGSVIALNDHK-LSELNGGMEEEFT 580

Human   586 MARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 650
            ||||:||||||||||||||||||||.|.|:.|||.|:|:|||:||:|||||:|||||||||||||
Zfish   581 MARLFISKMKSEVKSLVNRSKQLESTQSDTMRKMQANEKELASCQMLISQHQAKIKSLTDYMQNM 645

Human   651 EQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 715
            |||:||||||.|||:||||||.|:|:|||||..||||||::|:|||||||||||||||||||.||
Zfish   646 EQKKRQLEESHDSLTEELAKLHAEERMHEVSVLDKEKEHMSRMQDAEEMKKALEQQMESHRETHQ 710

Human   716 KQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 780
            ||||||||||||||:|:||::|:||.|:|||:||.|||.||:.|||:::.:|:|||.||:|:|||
Zfish   711 KQLSRLRDEIEEKQRILDELKDVNQALELEQKKLMSDYEKLQQEDQKKDERLQKLLFLNEKKEQA 775

Human   781 REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLT 845
            :||||||||||::||||||:|||||:||:..|:.:|||||.|:.|||.||||||.||||||||||
Zfish   776 KEDLKGLEETVAKELQTLHDLRKLFIQDINNRIGRSVELDTDESGGSLAQKQKIIFLENNLEQLT 840

Human   846 KVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRA 910
            |||||||.||||||||||||||||||||||||.|||||:||||:||||||:||||||||||.:||
Zfish   841 KVHKQLVHDNADLRCELPKLEKRLRATAERVKILESALREAKESAMRDRKKYQQEVDRIKEVIRA 905

Human   911 KNMARRAHSAQIAKPIRPG-HYPASSPTAVHAIRGGGGSSSNSTHYQ 956
            ||.:||.|:||||||||.| |:|.:|.:..|::|  ||:.|...|:|
Zfish   906 KNQSRRNHTAQIAKPIRAGHHHPVASASPGHSVR--GGTPSPRRHHQ 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF5C	NP_004513.1	KISc_KHC_KIF5	6..327	CDD:276820	298/320 (93%)
		Microtubule-binding	174..315		137/140 (98%)
		PRK03918	<412..907	CDD:235175	375/494 (76%)
		Khc_CBD_cc	836..905	CDD:467880	63/68 (93%)
		Globular	859..956		69/97 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	911..957		24/47 (51%)
kif5c	NP_001116747.1	KISc_KHC_KIF5	6..326	CDD:276820	298/320 (93%)
		PRK02224	403..>917	CDD:179385	385/514 (75%)
		Khc_CBD_cc	831..900	CDD:467880	63/68 (93%)