Protein Alignment emp and SCARB1

DIOPT Version :9

• Sequence 1: NP_726504.2
• Gene: emp / 37999
• FlyBaseID: FBgn0010435
• Length: 551
• Species: Drosophila melanogaster
• Sequence 2: NP_001354910.1
• Gene: SCARB1 / 949
• HGNCID: 1664
• Length: 552
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 157/485 - (32%)
• Similarity: 243/485 - (50%)
• Gaps: 44/485 - (9%)

  Fly    50 KWWITIVVAAALIIGGIVVACEFTVLIDAV-------VDRMVALRPGAKTFGWWAKPPVEPRISL 107
            :|     .|.||.:.|::.|....|:|..|       |.:.|.:.|.:.:|..|.:.|:...:|:
Human     8 RW-----AAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSV 67

  Fly   108 YIYNVTNADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKIYSFREDLSVGPED 172
            |.::|.|..:.| .|.|..|.|.|||||.|...|.||..|:|.|:|:...:.:.|:...|.|.|.
Human    68 YFFDVMNPSEIL-KGEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSES 131

  Fly   173 DVVIVPNIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLWGYEDPLLKLAKDVVP 237
            |.:::|||.:|.|....::....|:|.|......|..:.|:..:||:::|||:|||:.|.....|
Human   132 DYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFP 196

  Fly   238 KEQKLPY-EEFGLLYGKNGTSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDACNTLAGTDG 301
              ...|: ::|||....|.:.|...||.|||.:|.|..::|.:||.:.:..|.:|.||.:.||.|
Human   197 --GMFPFKDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSG 259

  Fly   302 SIFPPHIDHDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFADVDSHPDNMCFCPA 366
            .::||.:..:..|..|..:.||.:.|:: ||......:|.|||..|:.:||:...:|.|..|||
Human   260 QMWPPFMTPESSLEFYSPEACRSMKLMY-KESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCP- 322

  Fly   367 GKPSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKHQFFFDVQPKMGTTL 431
                |..:|:.|||.|::.:|:.||.|||..||..|...|.|:. |.:|.|..|.|:.|..|..:
Human   323 ----CLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLH-PNQEAHSLFLDIHPVTGIPM 382

  Fly   432 RVRARIQINLAVSQVFDIKQVANFPDIIFPILWF-EEGI---DNLPDEVTDL------MRFAEQV 486
            ....::|::|.:..|..|.|......::.|:||| |.|.   :.|....|.|      |.:|:.|
Human   383 NCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYV 447

  Fly   487 PPKIRVALIVGLCALGVILLLLSTFCLIRN 516
                       |.|||.:|||:...|.||:
Human   448 -----------LLALGCVLLLVPVICQIRS 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emp	NP_726504.2	CD36	58..511	CDD:279474	153/470 (33%)
SCARB1	NP_001354910.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148210
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3236
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	1	1.000	-	-		mtm8581
orthoMCL	1	0.900	-	-		OOG6_103616
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.810