DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment emp and RGD1565355

DIOPT Version :9

Sequence 1:	NP_726504.2	Gene:	emp / 37999	FlyBaseID:	FBgn0010435	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_001102688.1	Gene:	RGD1565355 / 499985	RGDID:	1565355	Length:	472	Species:	Rattus norvegicus

Alignment Length:	480	Identity:	145/480 - (30%)
Similarity:	237/480 - (49%)	Gaps:	39/480 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 IVVAAALIIGGIVVACEFTVLIDAVVDRMVALRPGAKTFGWWAKPPVEPRISLYIYNVTNADDFL 119
            |:.|...:.|||::... .:||:..:.|.|.|..|...|..|.|.........:|::|.|.::..
  Rat    14 IIGAVLAVFGGILMPVG-DLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEEVA 77

  Fly   120 SNGSKAIVDEVGPYVYSETW-EKVNIVEN-DNGTLSYNLRKIYSFREDLSVGPEDDVVIVPNIPM 182
            .|.||..|.:.|||.|...: .|.||.:: .:.|:|:.......|...||||.|:|...|||:.:
  Rat    78 KNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTENDNFTVPNLAV 142

  Fly   183 LSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLWGYEDPLLKLAKDVVPKEQKLPY--- 244
            .:|....:::  |::..:.:::...|...|...|:.:|||||:||.|.|          :||
  Rat   143 AAAPHIYQNS--FIQGVLNNLIKKSKSSMFQTRSLKELLWGYKDPFLSL----------IPYPIS 195

  Fly   245 EEFGLLYGKNGTSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDACNTLAGTDGSIFPPHID 309
            ...|:.|..|.|......|..|.|:|.:..|||.:.|:.:|.:|.: .|:.:.|||.:.|||.::
  Rat   196 TTVGVFYPYNNTVDGVYKVFNGKDNINKVAIIDTYKGKRNLSYWKS-YCDMINGTDAASFPPFVE 259

  Fly   310 HDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFADVDSHPDNMCFCPAG--KPSCS 372
            ..|.|..:..|:||.:..|||.||.... :|.|||..|...||....:|||.|||...  ..:|:
  Rat   260 KSRTLRFFSPDICRSIYAVFESEVNLKG-IPVYRFVLPVNAFASPLQNPDNHCFCTEKVISNNCT 323

  Fly   373 PNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKHQFFFDVQPKMGTTLRVRARI 437
            ..|:.::..|:...|:.:|.|||..|...:...::|:: |.:::|:.:.||:|..|.||:...|:
  Rat   324 SYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIQGLN-PNEDEHRTYLDVEPITGFTLQFAKRL 387

  Fly   438 QINLAVSQVFDIKQVANF--PDIIFPILWFEEGIDNLPDEVTDLMRFAEQVPPKI-------RVA 493
            |:|:.|.....|:.:.|.  |.|: ||||..| ...:.||..::  |..||..||       ||.
  Rat   388 QVNILVKPARKIEALRNLKRPYIV-PILWLNE-TGTIGDEKVEI--FRNQVTGKINLLDLVERVL 448

  Fly   494 LIVGLCALGVILLLLSTFCLIRNSH 518
            |:||:.   :.:..:.::|..|:.:
  Rat   449 LVVGVL---MFVAFMISYCACRSKN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
emp	NP_726504.2	CD36	58..511	CDD:279474	142/468 (30%)
RGD1565355	NP_001102688.1	CD36	16..461	CDD:279474	142/467 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	1	1.000	-	-		mtm9056
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820