DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment emp and CG31741

DIOPT Version :9

Sequence 1:	NP_726504.2	Gene:	emp / 37999	FlyBaseID:	FBgn0010435	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_724088.2	Gene:	CG31741 / 35079	FlyBaseID:	FBgn0051741	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	124/494 - (25%)
Similarity:	227/494 - (45%)	Gaps:	33/494 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 RKWWITIVVAAALIIGGIVVACEFTVLIDAVVDRMVALRPGAKTFGWWAKPPVEPRISLYIYNVT 113
            :|.|:..:....|.| ||.:|..:..:....:..::.|.|.:..:..|...|.....:::::|.|
  Fly    11 QKIWVFSMGGLILAI-GIFLASAWPAVSRQWIRSLLPLAPNSFIYNRWVTTPTPVYSTVFLFNWT 74

  Fly   114 NADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKIYSFREDLSVGPEDDVVIVP 178
            |..|..:.|.|...:::|||.:|:...|.:: |.:...::|..::.:.|..:.|.|..|||||.|
  Fly    75 NPGDLNTEGVKPHFEQLGPYTFSDFKVKEDL-EWNQPQVTYFGKRTWHFLPEKSNGSLDDVVIAP 138

  Fly   179 NIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLW-GYEDPLLKLAKDVVPKEQKL 242
            :.|.|:|...|:...|.||..|...::.......:..:.||.|: ||.|.||...:.:  ....|
  Fly   139 HFPTLTAALYSRRLRRILRKVMNFTLNREGGATHMTHTAGQWLFDGYYDHLLDFVEQL--HSPLL 201

  Fly   243 P-YEE-FGLLYGKNG--TSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDACNTLAGTDGSI 303
            | |:. ||..|.:|.  |:....|::||..|:.:.|.:..:||......:..: |..:.|:.|.:
  Fly   202 PVYDNTFGWFYERNNSKTAEGNFTLHTGRGDLSQLGDLLLWNGENTTGFYPGE-CGKVNGSTGEL 265

  Fly   304 FPPHIDHDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFADVDSHPDNMCFCPAGK 368
            :.|:...|:...::..|..|.|.| |.||.:|.:.:..:|:........:....||..|||...:
  Fly   266 WSPYRTWDQPTTIFLPDAARYLNL-FPKENLTIDGIDVWRYESTNLTIDNGQLSPDTECFCLKNR 329

  Fly   369 PSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKHQFFFDVQPKMGTTLRV 433
             .|..||:.:.....::.|..:|.|||:|.|:..|....|:.|...| |..:..::|.:|..|.:
  Fly   330 -ECPRNGVLDYGPPAFNGPFYMSHPHFFLTDQMYRENTTGLQPEESE-HGMYVIMEPTLGIPLSL 392

  Fly   434 RARIQINLAV--SQVFDI-KQVANFPDIIFPILWFEEGIDNLPDEVTDLMRFAEQVPPKIRVALI 495
            |.::.|:..|  .:..|: |.||.  |...|:.......: |.:.:|.|::.|      :..|:|
  Fly   393 RGQLMISTKVVRDEAIDLFKNVAY--DHYAPLFTMRLHAE-LDEGLTKLLKLA------LNAAII 448

  Fly   496 -----VGLCALGVILLLLSTFCLIR---NSHRQSTLHLE 526
                 :||..||:.:::...|...:   :|.::...||:
  Fly   449 GMYTGIGLVLLGMSIVVTGIFITKKHKWHSEQRPDKHLQ 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
emp	NP_726504.2	CD36	58..511	CDD:279474	118/465 (25%)
CG31741	NP_724088.2	CD36	21..469	CDD:279474	118/464 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450715
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	7	6.850