DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment emp and crq

DIOPT Version :9

Sequence 1:	NP_726504.2	Gene:	emp / 37999	FlyBaseID:	FBgn0010435	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_001245823.1	Gene:	crq / 33219	FlyBaseID:	FBgn0015924	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	127/478 - (26%)
Similarity:	228/478 - (47%)	Gaps:	39/478 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 CTKLSSTYLRKWWITIVVAAALIIGGIVVACEFTVLIDAVVDRMVALRPGAKTFGWWAKPPVEPR 104
            |.|......||.|: ..:.:..::.||::...:..:.|.:|:..:.|:||...:..|.:.|:...
  Fly     2 CCKCCGETQRKVWV-FGLGSVFLLLGILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIPIY 65

  Fly   105 ISLYIYNVTNADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKIYSFREDLSVG 169
            :|.|::|.||.:|..:...|....|:|||.:.|..:|.|....||.|::|..|:.:.|..:.|.|
  Fly    66 LSFYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKHKKENYTFYDNATVAYYERRTWFFDPERSNG 130

  Fly   170 PEDDVVIVPNIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLW-GYEDPLLKLAK 233
            ..||:|...:....:...:.:...:.::..:..:::....|.:|...||:.:: ||:|.:.....
  Fly   131 TLDDMVTAAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQDNITDFLN 195

  Fly   234 DVVPKEQKLPYEEFGLLYGKNG--TSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDACNTL 296
            .....:..:||:.||.|..:|.  |.....|::||.|||...|.:.::||::....:.. .|..:
  Fly   196 LFNTTKIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNGKSETGFYEM-PCGIV 259

  Fly   297 AGTDGSIFPPHIDHDRILHVYDKDLCRLLPL----VFEKEVMTSNEVPGYRFTPPEWVFAD--VD 355
            .||.|.:|||.::.:..:.::..|.||.:.|    .:|...:|:.          :||..:  :|
  Fly   260 NGTTGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYENHGLTAT----------KWVGTEETLD 314

  Fly   356 S---HPDNMCFCPAGK-PSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEK 416
            |   :|:..|||...: ..|...|:.....|:..:||..|||||||||:|....|.|:.|. |||
  Fly   315 SGENYPNQACFCDEARFDECPKTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPE-KEK 378

  Fly   417 HQFFFDVQPKMGTTLRVRARIQINLAVSQVFDIKQVANFPDIIFPILWFEEGIDNLPDEVTDLMR 481
            |:||..|:|..|..::|..|||||:.:....|.........::.|:.||        |:..:|
  Fly   379 HEFFLAVEPITGVPVQVHGRIQINMMIEPDDDFDIYRGVQKVLMPMFWF--------DQYAEL-- 433

  Fly   482 FAEQVPPKIRVALIVGLCALGVI 504
             :.::..|.::|  :.|.:.|:|
  Fly   434 -SSELASKAKLA--INLSSYGII 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
emp	NP_726504.2	CD36	58..511	CDD:279474	122/460 (27%)
crq	NP_001245823.1	CD36	19..470	CDD:307331	122/460 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450718
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5605
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	9	8.800