Protein Alignment CG2736 and CD36

DIOPT Version :9

• Sequence 1: NP_611991.1
• Gene: CG2736 / 37998
• FlyBaseID: FBgn0035090
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_000063.2
• Gene: CD36 / 948
• HGNCID: 1663
• Length: 472
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 97/432 - (22%)
• Similarity: 169/432 - (39%)
• Gaps: 78/432 - (18%)

  Fly    63 YVFNVTNAEEFRSGRDSRLKVKEIGPIVYRI---VGFNDILDRNETNVRYRKHRYRVVEFLPEES 124
            ::|:|.|.:|... ..|.::||:.||..||:   ...|...|..:..|.:.:....:.|  |..|
Human    66 WIFDVQNPQEVMM-NSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFE--PSLS 127

  Fly   125 VAPDVLNWTITSTNNVILGAATKVKHTAPLAAFGFDAALM-------MEDIFVTDSVYYFLWEFT 182
            |..:..|:|:.   |:.:.||:.:....      |...::       ...:|...::...||.:.
Human   128 VGTEADNFTVL---NLAVAAASHIYQNQ------FVQMILNSLINKSKSSMFQVRTLRELLWGYR 183

  Fly   183 RPLLQTLSRISNIRPNVAVLYNALKEKEEVYTVNIGPKRGIENFFRIETLNGEVIIREQLPHTRQ 247
            .|.|..:.  ..:...|.:.|......:.||.|..| |..|.....|:|..|:        ....
Human   184 DPFLSLVP--YPVTTTVGLFYPYNNTADGVYKVFNG-KDNISKVAIIDTYKGK--------RNLS 237

  Fly   248 YDSNSCPFNVSGALDNSLFPPFVQPDTPLSIVAIESCRVLPLTYQRQERYNGLDTFRYTL----L 308
            |..:.|.. ::|. |.:.|||||:....|...:.:.||.:...::......|:..:|:.|    .
Human   238 YWESHCDM-INGT-DAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAF 300

  Fly   309 QSHQKPPG----CLD-------TSYGVKLPDGMFDVSQCVINDAPSAFSMPHFYGSSYNWSQHYE 362
            .|..:.|.    |.:       |||||      .|:|:|. ...|...|:|||..:|.:.|:..:
Human   301 ASPVENPDNYCFCTEKIISKNCTSYGV------LDISKCK-EGRPVYISLPHFLYASPDVSEPID 358

  Fly   363 GYTPNAEDHEPYILLEPVTGIPVTEKYRFQSNIPIPDLRRFSSRLSRFSNMMIPSFWYEFEMG-- 425
            |..||.|:|..|:.:||:||..:....|.|.|:.:....:.....:...|.::|..|.. |.|
Human   359 GLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLN-ETGTI 422

  Fly   426 ----------QLPGFVT-----SLMWINVNIVQHIQ---PYC 449
                      |:.|.:.     .::.::|.:|..:.   .||
Human   423 GDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYC 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2736	NP_611991.1	CD36	10..462	CDD:279474	97/432 (22%)
CD36	NP_000063.2	CD36	14..463	CDD:395898	95/429 (22%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000269|PubMed:1371676	93..120		5/26 (19%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000269|PubMed:20037584	460..472		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750