DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2736 and CG10345

DIOPT Version :9

Sequence 1:	NP_611991.1	Gene:	CG2736 / 37998	FlyBaseID:	FBgn0035090	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_650563.2	Gene:	CG10345 / 42017	FlyBaseID:	FBgn0027562	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	121/485 - (24%)
Similarity:	204/485 - (42%)	Gaps:	114/485 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 MPTMDSWINSPFGKLKNYVFNVTNAEEFRSGRDSRLKVKEIGPIVYRIVGFNDILDRNETN--VR 108
            :|.:|.:||.       |:||.||.:||.|||.|:|:::|:||.||:.|..|..:..||:|  :.
  Fly    59 LPPLDVYINV-------YMFNYTNVDEFTSGRASKLQLQEVGPYVYKEVLSNHNVTYNESNNTIT 116

  Fly   109 YRKHRYRVVEFLPEESVAPDVLNWTITSTNNVILGAATKVKHTAPLAAFGFDAAL-------MME 166
            |...|..|  |.||.||....:: .|.:.|..::|..|.....:..||.|..|..       |:|
  Fly   117 YSPKREYV--FAPERSVGDPKID-RIRAPNIPLMGVTTLASSLSMFAALGLSAITRQLNSQPMLE 178

  Fly   167 DIFVTDSVYYFLWEFTRPLLQTLSRISNIRPN------VAVLYNALKEKEE--VYTVNI-GPK-- 220
                 .||:.::|.:...|::..||..   ||      ..::....:|..|  |:.:|: .||
  Fly   179 -----MSVHDYMWGYEDHLVELASRFV---PNWIDFSSFGIMEKLFREGNESNVFNMNLPEPKDK 235

  Fly   221 ---------RGIENFFRIETLNGEVIIREQLPHTRQY--DSNSCPFN-VSGALDNSLFPPFVQPD 273
                     ||    :.::::|||...:..     ||  ::|....| :.|:.|.:|||..:..:
  Fly   236 YGMRMTDAPRG----YTVDSINGERGFKGW-----QYNEETNGTMCNRIWGSHDATLFPLDMDEN 291

  Fly   274 TPLSIVAIESCRVLPLTYQRQERYNGLDTFRYTLLQSHQKPPGCLDTSYGVK-----------LP 327
            ....:.....||.||:.:.|...:||||.|.:.:      .|...|:.....           |.
  Fly   292 DEFFLYRRTFCRRLPVKFNRTTTFNGLDAFEFVM------EPDSFDSEVDNANSSCYCKNNRCLK 350

  Fly   328 DGMFDVSQCVINDAPSAFSMPHFYGSSYNWSQHYEGYTPNAEDHEPYILLEPVTGIPVTEKY-RF 391
            .|:.:||.|..| .|.|.:.|||..:..:..:.::|..||........:::|..|.|:...: |.
  Fly   351 KGVGNVSPCYYN-IPLAITYPHFMHADPSLLEPFDGLQPNVSRFTSTFVVQPQLGAPMQGTHLRL 414

  Fly   392 QSNIPIPDLRRFSSRLSRFSNMMIPSFWYEFEMGQLPGFVTSLMWINVNIVQHIQPYCMVLFLVL 456
            |:|..:..: .|:..::.|.||::|                 |:|:::|    |...|:.|.|::
  Fly   415 QANQVVGKV-NFNRMMTPFENMILP-----------------LLWVDLN----IDVLCLTLRLLI 457

  Fly   457 --------------ALWSVLKAIRVACGDL 472
                          ||..:|..:...|..|
  Fly   458 HGIKWGFPLLQWSAALGMLLAGVYQLCSAL 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2736	NP_611991.1	CD36	10..462	CDD:279474	118/473 (25%)
CG10345	NP_650563.2	CD36	21..488	CDD:279474	121/485 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850