DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2736 and scarb2a

DIOPT Version :9

Sequence 1:	NP_611991.1	Gene:	CG2736 / 37998	FlyBaseID:	FBgn0035090	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_775366.1	Gene:	scarb2a / 192340	ZFINID:	ZDB-GENE-020419-29	Length:	531	Species:	Danio rerio

Alignment Length:	501	Identity:	131/501 - (26%)
Similarity:	209/501 - (41%)	Gaps:	80/501 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLCLILACVNVFLFVVSWGVDYRILVAREHIRFRQEMPTMDSWINSPFGKLKNY-VFNVTNAEE 72
            ::|.:.|....||..::...:...|.:| |:.|      .:|.|||.|......| .|||||.:|
Zfish    19 LILGIALLLAQVFQTMIQERIKKEITLA-ENSR------VLDGWINPPPPVYMQYFFFNVTNPDE 76

  Fly    73 FRSGRDSRLKVKEIGPIVYRIVGFNDILDRNETNVRYRKHRYRVVEFLPEESV--------APDV 129
            |.:|:: :.||.::||..||..       |...||.|.::..::....|:..|        .|:|
Zfish    77 FLAGKE-KAKVTQMGPYTYREY-------RPRENVTYLENGTKIFATNPKSFVFLRNMSAGDPEV 133

  Fly   130 LNWTITSTNNVILGAATKVK------HTAPLAAFGFDAALMMEDIFVTDSVYYFLWEFTRPLLQT 188
            ..  :|:.|..::....::.      .||.....|    .|...:|:..:|:..||.|..||
Zfish   134 DR--VTTVNIPMIAVMNELNSYSFFVRTAVSMYMG----SMGMGLFMNRTVHEILWGFKDPL--- 189

  Fly   189 LSRISNIRPNV----AVLYNALKEKEEVYTVNIGPKRGIENFFRIETLNGEVIIREQLPHTRQYD 249
            |:::..:||.|    .::||.....|..:..:.|.|..: |:.:|:|.||       :.....:.
Zfish   190 LTKLHAMRPEVDEHFGLMYNKNGTHEGEFVFHTGEKNYM-NYGKIDTWNG-------ISQMNWWS 246

  Fly   250 SNSCPFNVSGALDNSLFPPFVQPDTPLSIVAIESCRVLPLTYQRQERYNGLDTFRYTLLQSHQKP 314
            ||..  |:....|.|:|..|:.....|.|.|.:.||.:.|.|.|.....|:..||:........|
Zfish   247 SNQS--NMINGTDGSVFHTFLSRKELLYIFAADLCRSIHLGYVRDMEVKGIPAFRFAPPSDVLAP 309

  Fly   315 PGCLDTSYGVKLP------DGMFDVSQCVINDAPSAFSMPHFYGSSYNWSQHYEGYTPNAEDHEP 373
            |.....:.|..:|      .|:..||.| ...||...|.||||.:...:....||..||.|:||.
Zfish   310 PDENPANAGFCVPAGDCLGKGVLKVSVC-RQGAPIVVSFPHFYQADERYINAIEGMNPNEEEHET 373

  Fly   374 YILLEPVTGIPVTEKYRFQSNIPIPDLRRFSSRLSRFSNMMIPSFWYEFEMGQLPGFVTSLMWIN 438
            |:.:.|.||:|:....|.|.||.:..:|.|.:  ::|.|..|           .|     :|::|
Zfish   374 YLDINPTTGVPIRACKRAQLNIILKRVRGFPN--TKFLNETI-----------FP-----IMYVN 420

  Fly   439 --VNIVQHIQPYCMVLFLVLALWSVLKAIRVACGDLGYVVLFRKLC 482
              ..|.........:|.|::.:.|....|.:|.|.:..|||...:|
Zfish   421 ETATIDDESAAQMRMLLLIVTVVSNFPVIILALGVILLVVLIFLVC 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2736	NP_611991.1	CD36	10..462	CDD:279474	124/478 (26%)
scarb2a	NP_775366.1	CD36	30..463	CDD:279474	128/485 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582146
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950