DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3776 and MAIP1

DIOPT Version :9

Sequence 1:	NP_001286868.1	Gene:	CG3776 / 37996	FlyBaseID:	FBgn0035088	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001381884.1	Gene:	MAIP1 / 79568	HGNCID:	26198	Length:	291	Species:	Homo sapiens

Alignment Length:	264	Identity:	69/264 - (26%)
Similarity:	107/264 - (40%)	Gaps:	49/264 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RC---LGMARISLMRLQPRP--TVAASGGQEAGS----ISKPTQPVS-RSFASLPQEQDKKEQNA 61
            ||   ||.|      |.||.  .:|||.....||    :|.|..|.: .||.:.||.....|:..
Human    44 RCRLGLGAA------LFPRSARALAASALPAQGSRWPVLSSPGLPAAFASFPACPQRSYSTEEKP 102

  Fly    62 RESLNRLPRLMDFPEIVWPSALNSLKNWITIQ---FIIRPYFDSEFQLKDFIYGAKQALQVVSSK 123
            ::.......::.|...:         ||:..:   |:|..|||.||.:.:|..|||||...||..
Human   103 QQHQKTKMIVLGFSNPI---------NWVRTRIKAFLIWAYFDKEFSITEFSEGAKQAFAHVSKL 158

  Fly   124 LMGGDLDSLDNLVSPEAIAELRPVIQKLSMTQRRQLEIKESDIYLSFPYQVGIMFDDANDKLQKR 188
            |.....|.|:.||:.|.:..|:..:..|....:..|.....:|..:....:.|.:|:..    ::
Human   159 LSQCKFDLLEELVAKEVLHALKEKVTSLPDNHKNALAANIDEIVFTSTGDISIYYDEKG----RK 219

  Fly   189 FVEITMVF----------HVMRGLSEMRERGEEIPWNMGTLPEYQDKVFICNYRFVKEFTAGHQS 243
            ||.|.|.|          ..:||.|..:.:       :|.......::...:|.|.:|||.|.:.
Human   220 FVNILMCFWYLTSANIPSETLRGASVFQVK-------LGNQNVETKQLLSASYEFQREFTQGVKP 277

  Fly   244 DWTV 247
            |||:
Human   278 DWTI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3776	NP_001286868.1	Tim44	101..>144	CDD:298851	17/42 (40%)
MAIP1	NP_001381884.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147747
Domainoid	1	1.000	69	1.000	Domainoid score	I9603
eggNOG	1	0.900	-	-		E1_28IWR
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	70	1.000	Inparanoid score	I5323
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1056493at2759
OrthoFinder	1	1.000	-	-		FOG0006981
OrthoInspector	1	1.000	-	-		oto89411
orthoMCL	1	0.900	-	-		OOG6_108532
Panther	1	1.100	-	-	LDO	PTHR13333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5779
SonicParanoid	1	1.000	-	-		X5880
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790