DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RpL19 and RPL19

DIOPT Version :9

Sequence 1:	NP_476631.1	Gene:	RpL19 / 37995	FlyBaseID:	FBgn0285950	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_000972.1	Gene:	RPL19 / 6143	HGNCID:	10312	Length:	196	Species:	Homo sapiens

Alignment Length:	193	Identity:	147/193 - (76%)
Similarity:	168/193 - (87%)	Gaps:	0/193 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSLKLQKRLAASVLRCGKKKVWLDPNEINEIANTNSRQNIRKLIKDGLIIKKPVVVHSRYRVRK 65
            ||.|:||||||:||||||||||||||||.|||||.||||.|||||||||||:|||.||||.|.||
Human     1 MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRK 65

  Fly    66 NTEARRKGRHCGFGKRKGTANARMPTKLLWMQRQRVLRRLLKKYRDSKKIDRHLYHDLYMKCKGN 130
            ||.|||||||.|.||||||||||||.|:.||:|.|:|||||::||:|||||||:||.||:|.|||
Human    66 NTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGN 130

  Fly   131 VFKNKRVLMEYIHKKKAEKQRSKMLADQAEARRQKVREARKRREERIATKKQELIALHAKEDE 193
            ||||||:|||:|||.||:|.|.|:|||||||||.|.:|||||||||:..||:|:|...:||:|
Human   131 VFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEE 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL19	NP_476631.1	Ribosomal_L19e_E	4..165	CDD:238705	128/160 (80%)
RPL19	NP_000972.1	Ribosomal_L19e_E	4..167	CDD:238705	129/162 (80%)
RPL19	NP_000972.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..176		15/18 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159676
Domainoid	1	1.000	241	1.000	Domainoid score	I2254
eggNOG	1	0.900	-	-		E1_COG2147
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68105
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2668
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62202
OrthoDB	1	1.010	-	-		D1437042at2759
OrthoFinder	1	1.000	-	-		FOG0001969
OrthoInspector	1	1.000	-	-		oto91531
orthoMCL	1	0.900	-	-		OOG6_100773
Panther	1	1.100	-	-	LDO	PTHR10722
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1113
SonicParanoid	1	1.000	-	-		X979
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800