DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2790 and AT1G74250

DIOPT Version :9

Sequence 1:	NP_611986.2	Gene:	CG2790 / 37992	FlyBaseID:	FBgn0027599	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_177565.1	Gene:	AT1G74250 / 843765	AraportID:	AT1G74250	Length:	630	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	166/508 - (32%)
Similarity:	249/508 - (49%)	Gaps:	98/508 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RCYYEELELQRNANDGDIKSAYRKMALRWHPDKNPDRL----AEAKERFQLIQQAYEVLSDPQER 62
            ||:||.|.:.:.::..:|:|:||::||:.||||.....    |||..:||.:..||||||||:||
plant    10 RCHYEVLGISKESSPDEIRSSYRRLALQRHPDKLMKAAGLSEAEATAQFQELVHAYEVLSDPKER 74

  Fly    63 SWYDNHREQILRGKNSD-----YAENCLDVFQFFTSSCYKGYGDNEHGFYRVYTDVFVQIASEDL 122
            :|||:||.|||...:|.     ...:..|:|.||:.:.|.||.|...|||:||.|||..:...::
plant    75 AWYDSHRSQILFADHSSAGGSKSGGSVPDLFAFFSPTVYSGYSDTGKGFYKVYYDVFNSVYLNEI 139

  Fly   123 EFMD----KDDRLGMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCPYDVREIKERFILRK 183
            :|..    :.|.:..||..|:..|.|..|.. ||.:|..:.|...:.|:..|||.....|...|.
plant   140 KFARTLGLRMDSVREAPIMGNLESPYAQVTA-FYNYWLGFCTVMDFCWVDEYDVMGGPNRKSRRM 203

  Fly   184 VEKEMKKIVQAARKERNEEVRNLVNFVRKRDPRVQAYRRMLEERVEANRLKQEEKRKEQLRKRQE 248
            :|:|.||..:.|::|.|:.||.|..||:|||      :|:::..|:.|  .:.||:||:.|:|::
plant   204 MEEENKKSRKKAKREYNDTVRGLAEFVKKRD------KRVIDMLVKKN--AEMEKKKEEERERKK 260

  Fly   249 ELAAVRKNNVFNEGYEEQLKQLEQQYDSKSEDYTDEDENDDDGEDFDHEGGQEAEEYEVEYVDD- 312
            ::...|.....|  |||             .::....|.:|:|     .|..|.||.:    ||
plant   261 KMEKERLERAMN--YEE-------------PEWAKAHEGEDEG-----AGLSELEEED----DDA 301

  Fly   313 ------LYCVACNKTFKNAKARANHEESKKHNENVDRLCQEMEEEEDAFHNEPHE-DSLMGVQES 370
                  |||:.|:|.||:.|...|||:||||.|.|..|.:...:.|:  .||..| |..:...||
plant   302 KRKNEQLYCIVCSKKFKSEKQWKNHEQSKKHKEKVAELRESFTDYEE--ENEEEEIDGPLDSPES 364

  Fly   371 LEEL-QVSEDQISFDGVPSEEESSLAKRTKKNKKARKSAVKQAQAEGSDEPDEPI----EKKAIK 430
            :||| :..:::::.|   :||           :..:|..|.:|     ||.|:..    |.....
plant   365 VEELHEKLQEELNID---NEE-----------RDVKKEVVGEA-----DETDDEYFVAEEDMQGS 410

  Fly   431 SESEDEDWSKGKKASKKSKSKKTTTRKVKLLEQTVSEPNTKEATVAPKSGDED 483
            |||||||                  .::.||::.||....|:..|..|..|||
plant   411 SESEDED------------------DEMTLLKKMVSGQKNKQKNVVSKEEDED 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2790	NP_611986.2	DnaJ	3..66	CDD:278647	30/66 (45%)
		ZUO1	19..>252	CDD:227594	92/245 (38%)
		zf-C2H2_jaz	313..337	CDD:288983	13/23 (57%)
		C2H2 Zn finger	315..337	CDD:275371	11/21 (52%)
AT1G74250	NP_177565.1	DnaJ	11..78	CDD:278647	30/66 (45%)
		zf-C2H2_jaz	307..333	CDD:288983	14/25 (56%)
		C2H2 Zn finger	310..332	CDD:275371	11/21 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I2167
eggNOG	1	0.900	-	-		E1_KOG0717
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I1213
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D858842at2759
OrthoFinder	1	1.000	-	-		FOG0004881
OrthoInspector	1	1.000	-	-		oto4002
orthoMCL	1	0.900	-	-		OOG6_102227
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3443
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730