DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2790 and dnajc21

DIOPT Version :9

Sequence 1:	NP_611986.2	Gene:	CG2790 / 37992	FlyBaseID:	FBgn0027599	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_031750589.1	Gene:	dnajc21 / 100158606	XenbaseID:	XB-GENE-1008007	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	572	Identity:	231/572 - (40%)
Similarity:	320/572 - (55%)	Gaps:	68/572 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRCYYEELELQRNANDGDIKSAYRKMALRWHPDKNPDRLAEAKERFQLIQQAYEVLSDPQERSWY 65
            |||:||.|.::|:.:|.|:|.||||:|||||||||.|...||.|:|:|||.||:|:||||||:||
Frog     1 MRCHYEVLGVRRDCSDEDLKKAYRKLALRWHPDKNLDNSEEAAEQFKLIQAAYDVISDPQERAWY 65

  Fly    66 DNHREQILR-GKNSDYAENCLDVFQFFTSSCYKGYGDNEHGFYRVYTDVFVQIASEDLEFMDK-D 128
            ||||:.:|: |.:.:|.::.||:.|:||.:||.||||:|.|||.||..:|..|..|::|  :| |
Frog    66 DNHRDALLKGGVDGEYQDDSLDLLQYFTVTCYSGYGDDEEGFYSVYRHIFELIVKEEME--NKID 128

  Fly   129 DRLGMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCPYDVREIKERFILRKVEKEMKKIVQ 193
            ..|...|.||.|.|.|:.||..|||:||::.|.|.:.|...||.|:...||..|.:|||.||:..
Frog   129 GDLEEYPSFGDSQSDYDTVVHLFYAYWQSFCTAKNFAWKEEYDTRQASNRFEKRAMEKENKKVRD 193

  Fly   194 AARKERNEEVRNLVNFVRKRDPRVQAYRRMLEERVEANRLKQEEKRKEQLRKRQEELAAVRKNNV 258
            .|||||||.:|.||.||||||.||||:|:|:||: .|.:.|:.|:.:.|.:::|.:||
Frog   194 KARKERNELIRELVAFVRKRDKRVQAHRKMVEEQ-NAEKAKKVEELRRQQKRQQAKLA------- 250

  Fly   259 FNEGYEEQ-----------LKQLEQQYDSKSEDYTDEDENDDDGEDFDHEGGQEAEE-YEVEYVD 311
              |.|:||           |:|:|.||.::..|.:|:|..|.: |..|.:.|:.:|| .|.|..|
Frog   251 --EQYKEQSWMAVSELERELQQMEAQYGAQFGDRSDDDAEDTE-EQRDGQNGKASEEGEEEEMYD 312

  Fly   312 DLYCVACNKTFKNAKARANHEESKKHNENVDRLCQEMEEEEDAFHNEPHEDSLMGVQESLEELQV 376
            ||||.||:|.||..||..|||:||||.|.|..|.|::|.||:.|..        .|:|...:.|.
Frog   313 DLYCPACDKVFKTDKAMKNHEKSKKHREMVALLRQQLEAEEEEFSG--------SVEEEDSQAQN 369

  Fly   377 SEDQISFDGVPSEEESSLAKRTKKNKKARKSAV------KQA---QAEGSDEPDEPI------EK 426
            .|.:||......:|...|:|:.||.|:.:..|:      :||   ...|..|.:.|.      |:
Frog   370 GEAEISSGEEEIKEMPKLSKKQKKKKQQKSKALDDSTDGEQAIKDNPNGHREGNSPTLVSASEEQ 434

  Fly   427 KAIKSE--SEDEDWSKGKKASKKSKSKKTTTRKVKLLEQTVSEPNTKEATVAPKSGDEDLDPTKS 489
            ..:.|:  :|.|......|.:.|.|.||....| |..:|          ..||...:|:..|.
Frog   435 NGVASDPGTEAEPQIGNVKPAPKLKGKKAKEMK-KAAKQ----------AAAPLQDEENEAPL-- 486

  Fly   490 QHTCVTCRLVFDSKNKLFAHLKKTNHGVYIPK-AKPNVEGKPPGKAKGKRNK 540
              .|.||...|.::||||:|||.|.|.:..|. |..|.......|...::||
Frog   487 --LCNTCSTEFPTRNKLFSHLKTTGHALATPNPAASNTAPNSRSKKDKRKNK 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2790	NP_611986.2	DnaJ	3..66	CDD:278647	39/62 (63%)
		ZUO1	19..>252	CDD:227594	121/234 (52%)
		zf-C2H2_jaz	313..337	CDD:288983	15/23 (65%)
		C2H2 Zn finger	315..337	CDD:275371	13/21 (62%)
dnajc21	XP_031750589.1	PRK10767	2..>66	CDD:236757	40/63 (63%)
		ZUO1	4..>267	CDD:227594	132/274 (48%)
		PTZ00121	<167..423	CDD:173412	106/274 (39%)
		zf-C2H2_jaz	314..339	CDD:403410	16/24 (67%)
		C2H2 Zn finger	316..338	CDD:275371	13/21 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3191
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6752
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2838
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D407472at33208
OrthoFinder	1	1.000	-	-		FOG0004881
OrthoInspector	1	1.000	-	-		oto104199
Panther	1	1.100	-	-	LDO	PTHR44029
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160