DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15861 and pear1

DIOPT Version :9

Sequence 1:	NP_001286863.1	Gene:	CG15861 / 37990	FlyBaseID:	FBgn0035084	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	226	Identity:	58/226 - (25%)
Similarity:	81/226 - (35%)	Gaps:	72/226 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRRMVFLQLLLWAVVEGHYYYDYGYWEINEPSQLCSD-YEMLVVNTRQCVRRCNIVCLNGVCFED 65
            :|..:..:.|...||:..|...|         |.|.. ||    :..:||.||...|::|.|...
Zfish    67 TRHRITYKTLYRQVVKMDYRRRY---------QCCPGFYE----SRNKCVPRCTKECVHGRCVAP 118

  Fly    66 GSCPCADQYMAGNPDGLVCAAEC-----LPGCVAAGGYCAAPDLCVCREDRHYYFDPLSQKCR-- 123
            ..|.|.   |....|.  |::.|     .|||         ..||.|:....  .|.|:..|:
Zfish   119 DRCQCE---MGWRGDD--CSSSCDGQHWGPGC---------RRLCECQNGGE--CDVLTGNCQCP 167

  Fly   124 --HRAPRLLDPC----LG-------RC-THGNCS-SDGRCICAQGYELRDSLLHGQQCMPICDHN 173
              :......|||    .|       :| |.|.|: :.|.|:|.||:           ...:|:.:
Zfish   168 AGYTGQHCHDPCPVKWFGQGCRQECQCGTGGICNQTTGECVCKQGF-----------TGTLCEES 221

  Fly   174 CGPRAYCFAPNLCACRHKQHHYAHNGICSGN 204
            | ||     |..||.|..   ..:.|||.||
Zfish   222 C-PR-----PKRCAARCP---CQNGGICQGN 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15861	NP_001286863.1	None
pear1	XP_700533.4	EMI	29..96	CDD:284877	8/37 (22%)
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900