DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15861 and megf6b

DIOPT Version :9

Sequence 1:	NP_001286863.1	Gene:	CG15861 / 37990	FlyBaseID:	FBgn0035084	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	XP_009304569.1	Gene:	megf6b / 557764	ZFINID:	ZDB-GENE-101112-3	Length:	1589	Species:	Danio rerio

Alignment Length:	236	Identity:	60/236 - (25%)
Similarity:	76/236 - (32%)	Gaps:	87/236 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EINEPSQLCSDYEMLVVNTRQCVRRCNIVCLNGVCFEDGSCPCADQYMAG---NPDGLVCAAECL 89
            |:.|..:.|.|.:...|:...|..    .|:|    ..||..|  |..||   :.||..|.|  :
Zfish   179 ELKEDGKTCQDIDECQVHNGGCQH----TCVN----TRGSYHC--QCNAGSRLHVDGRTCIA--V 231

  Fly    90 PGCVAAGGYC--------AAPDLCVCREDRHYYFDP-----------------LSQKCR------ 123
            ..|....|.|        |....|.||.|  |..|.                 .||.|.
Zfish   232 QSCGVGNGGCEHFCVQQTAGHVQCRCRPD--YRLDADGKHCTLVNPCAEQNGGCSQMCHRDGAQA 294

  Fly   124 ----HRAPRL---------LDPC-LGR--CTHG--NCSSDGRCICAQGYELRDSLLHGQQCMPI- 169
                |...:|         :|.| ||:  |.||  |......|:|:..|||.   :.|:||..|
Zfish   295 RCECHPGYQLAEDGKTCEDIDECALGQTDCAHGCRNTRGSFMCVCSAAYELG---VDGKQCYRIE 356

  Fly   170 ------CDHNCGPRAYCFAPNLCACRHKQHHYAHNGICSGN 204
                  |||:.|           .|.|...|.....:||.|
Zfish   357 MEIVNSCDHDNG-----------GCSHHCEHSTAGPLCSCN 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15861	NP_001286863.1	None
megf6b	XP_009304569.1	EMI	33..102	CDD:284877
		FXa_inhibition	152..187	CDD:291342	2/7 (29%)
		vWFA	<184..227	CDD:294047	14/52 (27%)
		FXa_inhibition	234..270	CDD:291342	10/37 (27%)
		FXa_inhibition	276..311	CDD:291342	5/34 (15%)
		vWFA	<308..350	CDD:294047	13/44 (30%)
		FXa_inhibition	363..398	CDD:291342	10/35 (29%)
		vWFA	<396..436	CDD:294047
		FXa_inhibition	445..480	CDD:291342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900