DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tina-1 and ggact.2

DIOPT Version :9

Sequence 1:	NP_611983.2	Gene:	Tina-1 / 37989	FlyBaseID:	FBgn0035083	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_001004544.1	Gene:	ggact.2 / 447805	ZFINID:	ZDB-GENE-040912-8	Length:	191	Species:	Danio rerio

Alignment Length:	152	Identity:	62/152 - (40%)
Similarity:	81/152 - (53%)	Gaps:	11/152 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LFVYGALKYGQPSNSILASSGNGFAKFWCKATTTQKLPLVIATRYNIPFLLNKPGVGYYVTGEIY 78
            :||||.||.|||:...|..|.||.|:|...|.|.:..||||....|||||||.||.|..|.||||
Zfish     4 VFVYGTLKKGQPNYFRLIDSSNGQAEFITCARTVEPYPLVITGECNIPFLLNVPGSGQRVYGEIY 68

  Fly    79 EVDDRMLNSLDNLEDCEEIYTREMHDMNI--GVGEGTV-PCWVYLLQKYPENLLSLRYLSSYENS 140
            .||.:||..||..|:|.:.|.|.:..:.|  |.||..| ..:||...||..:.|:.....||:::
Zfish    69 SVDQKMLEFLDWFEECPDWYQRTLIQLEILKGNGETEVEEAFVYTKTKYEPDWLNKPTYDSYDSN 133

  Fly   141 TTHPYIMRHRRTHKHPAQDDLT 162
            ..|..        |:..::|:|
Zfish   134 GDHGL--------KYAYEEDMT 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tina-1	NP_611983.2	GGACT	14..130	CDD:399234	55/118 (47%)
ggact.2	NP_001004544.1	GGACT	4..112	CDD:283699	51/107 (48%)
		Substrate binding. /evidence=ECO:0000250	7..10		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..191
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2105
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4932
OMA	1	1.010	-	-		QHG45924
OrthoDB	1	1.010	-	-		D1389682at2759
OrthoFinder	1	1.000	-	-		FOG0002855
OrthoInspector	1	1.000	-	-		mtm6526
orthoMCL	1	0.900	-	-		OOG6_103544
Panther	1	1.100	-	-	O	PTHR12510
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4010
SonicParanoid	1	1.000	-	-		X2213
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.800