DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and CG34342

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	158/513 - (30%)
Similarity:	273/513 - (53%)	Gaps:	21/513 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VDLSPVQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLP 67
            |..:||.::|.:.|:.|||.:||:||||.||||.| ..|:::.::.|.|...:.:.||:..|...
  Fly    65 VSATPVTDFYSNATVLITGGTGFVGKVLTEKLLRS-FGLRKIYMLIRSKDNMSVQERLKGFFNES 128

  Fly    68 IFQRIKDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMN 132
            ||.|:::|.|::|.:|...:.|.:...|.:.......::....|||::.|::|....|.||||:|
  Fly   129 IFNRMREESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDIN 193

  Fly   133 LLGTRRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAIT 197
            :|||::.|::..|||.|::|:|:||.:|||::..:.|:|||.....|.:|::....|.:||:.:.
  Fly   194 VLGTKKILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMR 258

  Fly   198 PDLLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAG 262
            ..|:...|||||.:|:.||.||......||..|.||.||.....:|.|||.||:.||:|:...:.
  Fly   259 HCLIGQMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSA 323

  Fly   263 KGVIRSMICNGELKSEVIPVDIAINGLILLPYHNSLAEKRPL---------QIPVYNLTVDDAKK 318
            :|::|.:......|:.::|.|..:|.:|...:  .:|.:..|         ::||||. |.||..
  Fly   324 RGLVRCIYGKASCKANMVPADYVVNAMIATAW--DIARRFKLRESKVDGKSELPVYNY-VSDANN 385

  Fly   319 RTWKWIMDVGRDLGIKYPFEVGLWYPDGNMTSSKFYHTICTILFMW--LPAYLIDFLLLIFGQRR 381
            .||...|.:.|. |...||:..||.....:..||..|  |.|.|..  :|||::|.:.::.||:|
  Fly   386 ITWGQYMHLSRK-GFHEPFDKALWCFSYVIIPSKPLH--CAIAFFLHNIPAYILDLIAMVTGQKR 447

  Fly   382 FMIRVQTKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILG 446
            ...:...||:..::::.:|..:.|.|...:.:::.:.|...:|.:.:.|...::..||.:..:.|
  Fly   448 IYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSG 512

  Fly   447 GRQYVMKEPL--TSLPKSRIQLRFMYVLDRICKTMI-ISGLLYWVSQKLRVVDLFRSV 501
            .|:|..|:..  ..|.:.|...|.|.:|..:.||.. :|.::..:...||:..:...:
  Fly   513 IRRYFFKDSANDNKLQQRRTIYRRMLILHTLLKTTFGLSLIMCMLRVYLRIFKIMPKI 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	108/314 (34%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	20/90 (22%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	145/455 (32%)
		FAR-N_SDR_e	78..397	CDD:187547	111/322 (34%)
		Sterile	429..519	CDD:281068	20/89 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466758
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	9.000