DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and CG17562

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	159/509 - (31%)
Similarity:	259/509 - (50%)	Gaps:	53/509 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :|..::.||:|:|||:||:|||::||||.:. .:|.:.::.|||||...:.|:....|..:|:.:
  Fly     5 IQRCFRSKTVFLTGATGFLGKVVIEKLLRTT-EVKRIYVLIRPKRGVEIKDRIITWSKDAVFELL 68

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTR 137
            ...:||.|:||....||.....||:|....:.:.....||.|.|||::....|..|:.:|...|:
  Fly    69 LKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTRATK 133

  Fly   138 RALNVAKEMKQLEAFIHLSTAFCNCDQDVMY---EKVYEFPHKPEDL-------MRLAEWMDVKT 192
            ..:.:||||:|||||:|:||||.||   |:|   |..|     ||.|       :.:||.|..:.
  Fly   134 LMIQLAKEMRQLEAFVHVSTAFSNC---VIYNIKENFY-----PEHLNCSSDKVLAMAELMSDEL 190

  Fly   193 LDAITPDLLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGV 257
            ||.:...||...||||||:|.|||.::......:|:.|.||:::..|..||:.||:|||.||..:
  Fly   191 LDNMEQALLGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAI 255

  Fly   258 LIGAGKGVIRSMICNGELKSEVIPVDIAINGLILLPYHNSLAE-------KRPLQIPVYNLTVDD 315
            |.|..:||:|....:...::.::|||...| |.|.....::.|       :.||   :|.|...:
  Fly   256 LFGVARGVLRIATIDHHAEASLVPVDYCAN-LTLACTWKTIVEGNEMGTQETPL---IYQLAPIE 316

  Fly   316 AKKRTWKWIMDVGRDLGIKYPFEVGLWYPDGNM--------TSSKFYHTICTILFMWLPAYLIDF 372
            ..|.|....:....|.....|....:|||..:.        .::.||||        ||||..|.
  Fly   317 QNKITHGEFIRHALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHT--------LPAYFFDL 373

  Fly   373 LLLIFGQRRFMIRVQTKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDY 437
            .|.:.|::..:::|..||...|.:|..|..:||.|...:.:.:.:::...||||:..:...::..
  Fly   374 ALWLSGRKPRLVKVYQKIHKTLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWK 438

  Fly   438 EYMKVSILGGRQYVMKEPLT--SLPKSRIQLRFMYVLDRICKTMIISGLLYWVS 489
            ||...::.|.||::..|..|  |:.:.:..::.:.:|..     |:.|:|.:|:
  Fly   439 EYFVQALRGMRQFLGNEAPTPESIAQGKKLIKRLKLLHH-----ILQGVLCFVA 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	115/322 (36%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	25/88 (28%)
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	147/452 (33%)
		FAR-N_SDR_e	12..329	CDD:187547	116/329 (35%)
		FAR_C	362..452	CDD:176924	29/97 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466757
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	1	0.950	-	0	Normalized mean entropy	S3821
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	11	10.850