DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and far1

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	522	Identity:	181/522 - (34%)
Similarity:	290/522 - (55%)	Gaps:	34/522 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :.|||..|.:.||||:||||||||||||.||..:|...::.|||.|:||:.|:.:|....:|.|:
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTR 137
            ::::|:...::.....|:|...|.||.|..:.:|...|:|||.|||::....|:||:.:|:|.|:
Zfish    69 REDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQ 133

  Fly   138 RALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPDLLK 202
            :.:::|..||.||.|||:|||:.|||::::.|.||..|.....|:...||||.|.:..:||.||.
Zfish   134 KMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRLLG 198

  Fly   203 PHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKGVIR 267
            ..||||||:|.|||.||:....::.:.|.|||||..:..||.|||:||.|||:|:.|.||||::|
Zfish   199 ERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGILR 263

  Fly   268 SMICNGELKSEVIPVDIAINGLILLP-YHNSLAEKRPLQIPVYNLTVDDAKKRTWKWIMDVGRDL 331
            :|..:....::::|||:.||..:... |..|....||..:.|||.|........|      |.
Zfish   264 TMRASNNAVADLVPVDVVINTTLAAAWYSGSQRHARPRSLLVYNCTTGGINPFHW------GE-- 320

  Fly   332 GIKY---------PFEVGLWYPDGNMTSSKFYHTICTILFMWLPAYLIDFLLLIFGQRRFMIRVQ 387
             ::|         |.|.....|:.|:|::...:.....:....||:|.|..|.:.|:...|::..
Zfish   321 -VEYHVISTFKRNPLEQAFRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREPRMMKTI 384

  Fly   388 TKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILGGRQYVM 452
            |::...:.||::||:.||.:.:.:...:..::|:.|:::|..:...:...|||:...:|.::||:
Zfish   385 TRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTKKYVL 449

  Fly   453 KEPLTSLPKSRIQLRFMYVLDRICKTMIISGLLYW-----VSQKLR-----VVDL---FRSVFHS 504
            .|.|:.||.:|..|..:..:.....|:::  :|.|     .||..|     ||.|   |.|.|.:
Zfish   450 NEELSGLPAARKHLNKLRNIRYTFNTVLV--VLIWRIFIARSQMARNIWYFVVSLCFKFLSYFRA 512

  Fly   505 ST 506
            |:
Zfish   513 SS 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	128/306 (42%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	23/88 (26%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	131/330 (40%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	23/89 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593272
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950