DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and CG10097

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001027182.1	Gene:	CG10097 / 3771756	FlyBaseID:	FBgn0038033	Length:	501	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	146/501 - (29%)
Similarity:	265/501 - (52%)	Gaps:	29/501 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SPVQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQ 70
            |.:..:|||||:||||.:|.:|||::||||.:. .:|.:..:.|.|||:..|.|.|...|..:|:
  Fly     3 SEIISFYKDKTVFITGGTGLLGKVVVEKLLRAT-DVKRIYFLVRTKRGEKMEARFESWKKDQVFE 66

  Fly    71 RIKDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLG 135
            .:.::.|..|:::|...||.....||:|....:.:.....::.|.||:::.|..|..|:.:|...
  Fly    67 VLLNKNPLALEKMTPISGDCCAPDLGISETDRRILAAEVQVLIHGAASVRFEEPLEHAVVINTRA 131

  Fly   136 TRRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDL-------MRLAEWMDVKTL 193
            .|....:||||:.||:|:|:||||.||..|.:.|:.|     ||.|       :.:...:..:|.
  Fly   132 VRLITQLAKEMRLLESFVHVSTAFSNCVVDQIQERFY-----PEHLSCPVDKVLDMHNSVSSETF 191

  Fly   194 DAITPDLLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVL 258
            :.:.|.|:...||||||:|.|.|.::::..:.:||.|.||:|:.....||:.||||.:.|...::
  Fly   192 EKMAPALIGKFPNTYTYTKALGEQVIQEEAKGLPVGIFRPAIILSTFKEPVQGWVDGLQGLIAMI 256

  Fly   259 IGAGKGVIRSMICNGELKSEVIPVDIAINGLILLPYHNSLAEKR-----PLQIPVYNLTVDDAKK 318
            .....|.:..::.|.::.:.::|||..:|..|......:...|:     |   |:|..|..::..
  Fly   257 FATAYGFVHLLLVNLKVNAPIVPVDYCVNVAIASAVQIAKISKQNKNGPP---PIYAFTPSESNL 318

  Fly   319 RTWKWIMDVGRDLGIKYPFEVGLWYPDGNMTSSKFYHTICTILFMWLPAYLIDFLLLIFGQRRFM 383
            .|::.:..:....|::.|....:|||..:.|...:.:.|..:.:..||.||:|.:|.:.||:..|
  Fly   319 VTYEDLAGLCYQNGLEVPNAKMIWYPFTHCTRCPYLYNIGILFYHMLPGYLLDIVLRLKGQKPMM 383

  Fly   384 IRVQTKIAVGLEVLQFFTTRSW--DFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILG 446
            |:...|:..|:..|..|:.:::  |.|:|:  ::::.:...::.:|..:...::..||....:.|
  Fly   384 IKSYHKVHEGMRSLLPFSRKTFTMDMKNTN--EMWQSMSPEEKEMFNFDMSTLNWKEYFTCLMDG 446

  Fly   447 GRQYVMKEPLT--SLPKSRIQLRFMYVLDRICKTMIIS--GLLYWV 488
            .|.|:.|:..|  |:.:.:..|:..||||||.||::::  |...|:
  Fly   447 IRLYLFKDLRTPDSVAEGKRILKRFYVLDRILKTVLVTLFGGFIWL 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	97/317 (31%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	23/90 (26%)
CG10097	NP_001027182.1	PLN02996	1..453	CDD:215538	132/460 (29%)
		FAR-N_SDR_e	12..330	CDD:187547	98/326 (30%)
		Sterile	363..453	CDD:281068	23/91 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466764
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890