DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and Sgp

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001260257.1	Gene:	Sgp / 34188	FlyBaseID:	FBgn0032055	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	149/516 - (28%)
Similarity:	264/516 - (51%)	Gaps:	33/516 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :.::||||::|:||.:||:|||::||||.|. .::.|.::.|||:.:..|.|.:.....|:|:.:
  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRST-DVRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTR 137
            ...:||.||.||...||.:...||||....:.||.:..::.|.||:::....|:.|:::|...||
  Fly    69 LKAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALNINTRATR 133

  Fly   138 RALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDL-------MRLAEWMDVKTLDA 195
            ..:.:|||||.||||:|:||||.||....:.|:.|     ||.|       :...|.:....||.
  Fly   134 LMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFY-----PEHLTCPAAKVLEFNETLSPDLLDK 193

  Fly   196 ITPDLLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIG 260
            :.|.|:...||||||:|.|||.:::...:.:|:.:.||:|:.....||:.||:||::|...::.|
  Fly   194 MAPALMGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYG 258

  Fly   261 AGKGVIRSMICNGELKSEVIPVDIAINGLILLPYH----------NSLAEKRPLQIPVYNLTVDD 315
            ...|::|.:..|.:..:.::|.|...|..:...:.          :.||.|:|  .|:|.|....
  Fly   259 NTYGILRLLYVNPKADAIIVPGDYCANVALASGWQVAKNSESRSSSQLAAKKP--PPIYTLATTK 321

  Fly   316 AKKRTWKWIMDVGRDLGIKYPFEVGLWYPDGNMTSSKFYHTICTILFMWLPAYLIDFLLLIFGQR 380
            :...|:...:.:|.......|....:|||..:.|:..:...:..|.:..:|.:..|.||.|.|::
  Fly   322 SNSITFGKAVKLGIHHNHTIPVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGKK 386

  Fly   381 RFMIRVQTKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSIL 445
            ..::|...||...|.:|..|..::::....:..|::..:...||.||..:...::..||....:.
  Fly   387 PILMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNWEEYFTRILS 451

  Fly   446 GGRQYVMKEPLTSLPKSRIQLRFMYVLDR-----ICKTMIISGLLYWVSQKLRVVDLFRSV 501
            |.|.::.||...:|.:::.:|...|:|.|     :|..:   |.:.|:...:...:..||:
  Fly   452 GMRVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLAL---GKIVWILYSVIANNYIRSI 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	105/322 (33%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	21/88 (24%)
Sgp	NP_001260257.1	PLN02996	1..449	CDD:215538	135/451 (30%)
		FAR-N_SDR_e	12..333	CDD:187547	106/328 (32%)
		FAR_C	367..457	CDD:176924	21/89 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466763
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	1	0.950	-	0	Normalized mean entropy	S3821
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	11	10.850