DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and CG4020

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001259264.1	Gene:	CG4020 / 31522	FlyBaseID:	FBgn0029821	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	159/485 - (32%)
Similarity:	269/485 - (55%)	Gaps:	11/485 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :.|.::|:.||:||||||:||.|:||||.||..|..:.::.|||:|...|.||:..::..:::|:
  Fly     3 IPEAFEDQEIFVTGASGFVGKALIEKLLRSCPKLGRIYVLMRPKKGHTIEERLQLQWESRLYERL 67

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLS-GESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGT 136
            :.|:|....::....|||  :||||. |.:......|.|||:|.||:::.:..|..||.:|..||
  Fly    68 RREQPNARSKLVAIAGDV--EQLGLGIGSADLERLRNVNIVYHSAASVRFDDALSTAILLNTRGT 130

  Fly   137 RRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPDLL 201
            ...:.:|.|..:|:||:|:||.:.|.....:.|:||.........::|||..|.:.||.......
  Fly   131 HELVKLALEWPKLKAFVHVSTTYSNPGVLEVEERVYPPLADWRTTIKLAETYDAEILDIFNLKYG 195

  Fly   202 KPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKGVI 266
            ...|||||::|.|||.:|.::.:.:|:.|.|||||...:.||:|||.||.|||||:|:..|.|::
  Fly   196 NFQPNTYTFTKSLAEQVVNEYRDRLPIFIFRPSIVVSTIEEPVPGWADNFNGPTGLLVACGVGIL 260

  Fly   267 RSMICNGELKSEVIPVDIAINGLILLPYH---NSLAEKRPLQIPVYNLTVDDAKKRTWKWIMDVG 328
            ||..|:..:.::.:|.||....||...|.   .|.:..:...:.|.|....:....|...::|:|
  Fly   261 RSQNCDPNIVADFVPADIVARTLITSVYKFMGESKSRAKDSDLYVVNCATANISPITMGEVIDIG 325

  Fly   329 RDLGIKYPFEVGLWYPDGNMTSSKFYHTI--CTILFMWLPAYLIDFLLLIFGQRRFMIRVQTKIA 391
            :....|.|||..||.|.|.||:....|.:  ||:..  |.|.::|.||.::.::.|::::|.:|.
  Fly   326 KTFIRKNPFEKTLWLPGGGMTTCPVLHFVRFCTMHL--LMAIVVDTLLRLYNEKPFLMKLQRRIF 388

  Fly   392 VGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFK-INTDDVDDYEYMKVSILGGRQYVMKEP 455
            .....||.|....|.|::.:|..::..:.:.:...|. :...:::..|:.:..|.|.:::::||.
  Fly   389 AAFSALQVFAMTEWHFQNDNFRALHDVVPANEVSNFGFMQHANINYTEFFQHGIRGAKEFLLKES 453

  Fly   456 LTSLPKSRIQLRFMYVLDRICKTMIISGLL 485
            ..|...:|.:::..||||.:|:.::.|.||
  Fly   454 PESSSAARFRVKIFYVLDFLCRGIVYSFLL 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	111/309 (36%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	18/89 (20%)
CG4020	NP_001259264.1	FAR-N_SDR_e	12..333	CDD:187547	115/322 (36%)
CG4020	NP_001259264.1	FAR_C	359..450	CDD:176924	18/92 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466741
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900