Protein Alignment CG30427 and Far1

DIOPT Version :10

• Sequence 1: NP_726498.1
• Gene: CG30427 / 37986
• FlyBaseID: FBgn0043792
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001011933.1
• Gene: Far1 / 293173
• RGDID: 1306647
• Length: 515
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 174/524 - (33%)
• Similarity: 292/524 - (55%)
• Gaps: 41/524 - (7%)

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :.|||:.|.|.:|||:||:|||||||||.||..:..|.::.|.|.|:.|:.|:||:....:|.|:
  Rat     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRL 68

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTR 137
            :||.|:..:::.....::|..:|.||.|..:.:.::||::||.|||::...|||||:.:|::.||
  Rat    69 RDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   138 RALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPDLLK 202
            :.:.:|::||.||.|:|:|||:..|::..:.|.||..|..|:.|:...||||...::.|||.|:.
  Rat   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIG 198

  Fly   203 PHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKGVIR 267
            ..||||.|:|.|||.:|:.....:.|.|.|||||..:..||.|||:||.|||:|:.|.||||::|
  Rat   199 DRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   268 SMICNGELKSEVIPVDIAINGLILLPYHNSLAEKRPLQIPVYNLTVDDAKKRTWKWIMDVGRDLG 332
            :|..:....::::|||:.:|..:...:::.:  .||..|.|||.|........|..:.|.
  Rat   264 TMRASNNALADLVPVDVVVNTSLAAAWYSGV--NRPRNIMVYNCTTGSTNPFHWGEVGDY----- 321

  Fly   333 IKYPFEVGLWYPDGNMTSSKFYHTIC------TILFMW------LPAYLIDFLLLIFGQRRFMIR 385
            :.:.|:.       |..:..|.|...      .:|..|      :||.|:|..|.:.||:.:|::
  Rat   322 LNHSFKT-------NPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMK 379

  Fly   386 VQTKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILGGRQY 450
            ..|::...:..|::||:.||.:.:.:...:..:|...|::.|.|:...:...||::...:|.::|
  Rat   380 TITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKY 444

  Fly   451 VMKEPLTSLPKSRIQLRFMYVLDRICKTMIISGLLYW-----VSQKLR-----VVDL---FRSVF 502
            |:.|.::.||.:|..|..:..:.....|:::  :|.|     .||..|     ||.|   |.|.|
  Rat   445 VLNEEMSGLPAARKHLNKLRNIRYGFNTILV--ILIWRIFIARSQMARNIWYFVVSLCYKFLSYF 507

  Fly   503 HSST 506
            .:|:
  Rat   508 RASS 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_726498.1	FAR-N_SDR_e	15..321	CDD:187547	122/305 (40%)
		Sterile	362..453	CDD:460779	24/96 (25%)
Far1	NP_001011933.1	FAR-N_SDR_e	11..330	CDD:187547	125/332 (38%)
		Sterile	371..447	CDD:460779	18/75 (24%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		15/57 (26%)