DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30427 and far1

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	529	Identity:	182/529 - (34%)
Similarity:	294/529 - (55%)	Gaps:	48/529 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRI 72
            :.|:|:.|.:.||||:||||||||||||.||.::|.|.::.|||..:.|..|:.||....:|.|:
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFDRL 68

  Fly    73 KDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTR 137
            :||:||..::|.....::|..:|.||.|....:.:..:||||.|||::...:||||:.:|::.||
Frog    69 RDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIATR 133

  Fly   138 RALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPDLLK 202
            :.|.:|:::|:||.|||:|||:.||::..:.|.||..|..|:.|:...||||...::.|||.|:.
Frog   134 QLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPVDPKKLIESLEWMDDGLVNDITPKLIG 198

  Fly   203 PHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKGVIR 267
            ..||||||:|.|||.:|:.....:.:.|.|||||..:..||.|||:||.|||:|:.|.||||::|
Frog   199 DRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   268 SMICNGELKSEVIPVDIAINGLILLPYHNSLAE-KRPLQIPVYNLTVDDAKKRTWKWIMDVGRDL 331
            :|..:....:::||||:.:|..:...:::.:.. .||..|.|||.|........|      |.
Frog   264 TMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRYSRPRNILVYNCTTGGTNPFHW------GE-- 320

  Fly   332 GIKY---------PFEVGLWYPDGNMTSSK-FYHTICTILFMWL------PAYLIDFLLLIFGQR 380
             ::|         |.|.....|:.|:||:. .||       .|:      ||:|.|..|.|.|:.
Frog   321 -VEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYH-------YWIAVSHKAPAFLYDVYLRITGRS 377

  Fly   381 RFMIRVQTKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSIL 445
            ..|::..|::...:.:|::||:.||.:.:.:...:..:|...|::.|..:...:...|||:...:
Frog   378 PRMMKTITRLHKAMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCM 442

  Fly   446 GGRQYVMKEPLTSLPKSRIQLRFMYVLDRICKTMIISGLLYW-----VSQKLR-----VVDL--- 497
            |.::||:.|.::.||.:|..|..:..:.....|:::  :|.|     .||..|     ||.:
Frog   443 GTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILV--VLIWRVFIARSQMARNIWYFVVSMCFK 505

  Fly   498 FRSVFHSST 506
            |.|.|.:|:
Frog   506 FLSYFRASS 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	128/306 (42%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	24/94 (26%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020