DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30427 and si:dkey-97m3.1

DIOPT Version :9

Sequence 1:	NP_001246512.1	Gene:	CG30427 / 37986	FlyBaseID:	FBgn0043792	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001076558.1	Gene:	si:dkey-97m3.1 / 100034578	ZFINID:	ZDB-GENE-060503-367	Length:	515	Species:	Danio rerio

Alignment Length:	515	Identity:	170/515 - (33%)
Similarity:	295/515 - (57%)	Gaps:	17/515 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSPVQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIF 69
            :..:.|:|..|.:.||||:|||||||:||||.||..:..:.|:.|||.|::...|:::|.|..:|
Zfish     1 MGSISEWYAGKNVLITGATGFMGKVLVEKLLRSCPDVNALYILVRPKAGQSMSERVQDMMKCKLF 65

  Fly    70 QRIKDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLL 134
            .|::::.||..:::.....::....|.:|.:.::.:|...:||||.|||::.:..|:.|:.:|::
Zfish    66 DRVREDNPEFHQKIIAISSELMQPGLAISAQDVETLTSRVHIVFHCAATIRFDEPLKHALQLNVM 130

  Fly   135 GTRRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPD 199
            .|::.|::|::|:||:||||:|||:.||::..:.|.:|..|.:|..|:...||||...:..|||.
Zfish   131 ATQQLLSLAQQMQQLQAFIHISTAYANCNRRHIDELIYPPPVEPRKLIDSLEWMDESIIRDITPR 195

  Fly   200 LLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKG 264
            |:...||||||:|.|||.:|:.....:.|.|.|||||..:..||.|||:||.|||:||.|.||||
Zfish   196 LIGDWPNTYTYTKALAECVVQQESAKLNVGIVRPSIVGASWQEPFPGWIDNFNGPSGVFIAAGKG 260

  Fly   265 VIRSMICNGELKSEVIPVDIAINGLILLPYHNSLAEKRPLQIPVYNLTVDDAKKRTWKWIMDVGR 329
            ::|:|..:.:..:::||||:.||..:...::.  |..:|....|||.|........|..|.....
Zfish   261 ILRTMRASNDAVADLIPVDVVINLTLAAGWYT--AVNKPKTALVYNCTTGGINPFHWGEIEHHVM 323

  Fly   330 DLGIKYPFEVGLWYPDGNMTSSKFYHTICTILFMWLPAYLIDFLLLIFGQRRFMIRVQTKIAVGL 394
            ....:.|.|.....|:.|:||:...:....::...:||.|.|.||.:.|.:..|:|:..::...:
Zfish   324 STFKRNPLEQAFRRPNANITSNYLIYQYWILVSHKVPALLYDLLLRLSGHKPQMMRIFNRLHKAI 388

  Fly   395 EVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILGGRQYVMKEPLTSL 459
            .:|::|:::.|::.|.:...:..:|.:.||:||..:...::..||::...:|.::||:.|.::.:
Zfish   389 GLLEYFSSQDWEWNSDNMNMLMAQLSTDDRKIFNFDVRQLNWPEYIENYCIGTKKYVLNEDMSDI 453

  Fly   460 PKSRIQLRFMYVLDRICKTMIISGLLYW-----VSQKLR-----VVDL---FRSVFHSST 506
            |.:|..||.:..:.....|:::  :..|     .||..|     ||.|   |.|.|.:|:
Zfish   454 PAARQHLRKLRNIRYTFNTVLL--VFIWRVFIARSQMARNIWYFVVSLCFKFLSYFRASS 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30427	NP_001246512.1	FAR-N_SDR_e	15..321	CDD:187547	120/305 (39%)
CG30427	NP_001246512.1	Sterile	364..453	CDD:281068	23/88 (26%)
si:dkey-97m3.1	NP_001076558.1	PLN02996	2..446	CDD:215538	152/445 (34%)
		FAR-N_SDR_e	11..330	CDD:187547	122/320 (38%)
		Sterile	357..447	CDD:281068	23/89 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750