Protein Alignment pain and Ankrd31

DIOPT Version :10

• Sequence 1: NP_611979.1
• Gene: pain / 37985
• FlyBaseID: FBgn0060296
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001357857.1
• Gene: Ankrd31 / 625662
• MGIID: 5006716
• Length: 1857
• Species: Mus musculus
• Alignment Length: 523
• Identity: 105/523 - (20%)
• Similarity: 178/523 - (34%)
• Gaps: 141/523 - (26%)

  Fly    47 IYEKALSTPGCRDFIEACIDHGSQVNYIN----KKLDKAAIS--YAADSRDPGNLAALLKYRPGN 105
            :|:.||...  .|.:..||.:|..||..:    ..|.:|:|.  |.|       ::.|||  .|.
Mouse   480 LYKAALHND--VDLVRCCIKNGENVNQPSYDGWTALHEASIGGYYQA-------VSELLK--GGA 533

  Fly   106 KVQVDRKYGQLTPLNSLAKNLTDENAPDVYSCMQLLLDYGASPNIVDQGEFTPLHHVLRKSKVKA 170
            .|.|..|| |:|||:....|..       |...:|||..||.|
Mouse   534 DVNVKGKY-QITPLHDAVMNRH-------YKVAELLLMSGADP---------------------- 568

  Fly   171 GKKELIQLF-LDHPELDIDSYRNGEVRRLLQAQFPELK---LPEERHTGPEIDIQTLQRTLRDG- 230
                   || .||....:|..::..:..||....|:.|   |..:|::.....::.:.:..:..
Mouse   569 -------LFRSDHGTCALDEAKDSSMETLLMKYIPQQKKCHLSAQRNSTDPAHVEDMFQNKKPKL 626

  Fly   231 ----------DETLFEQQFAEYLQNLKGGADNQLNAHQE---EYFGLLQESIKRGRQRAFDVILS 282
                      ||. |::|...:|:..||  .|.|...:|   |:......:.|.|:.. .:.:.:
Mouse   627 SSNNYTEFICDEN-FDRQEPGHLEINKG--SNNLLMSKEYVCEHCQKDSNTTKFGKSN-LNSVKN 687

  Fly   283 TGMDINSRPGRAN-----------EANLVE----------TAVIYGNWQALERLLKEP----NLR 322
            :..:::.|.|:.|           :.||.:          ..::.....|::.|...|    .|.
Mouse   688 SRTNVSKRKGQKNRQQKKTQVDDRDCNLSQKIGTSSFRRTNKLLTQQQHAVQTLSDLPEESFELS 752

  Fly   323 LTPDSKLLNA--------VIGRLDEPPYDGSSHQRCFELLINSDRVDINEADSGRLVPLF----- 374
            .|..|.|.|.        |..:.|....|.|..|. .|.:..::...::|..|.:.:.|.
Mouse   753 TTTLSSLENGIGYNEACLVSKKSDTHVLDSSDGQE-LESVDQTEAASVSELSSYKEIKLLPVTTH 816

  Fly   375 ---------FAVKYR---NTSAMQKLLKNGAYIGSKSAF--GTLPIKDMPPEVLEEHFDSCITTN 425
                     ::..|:   |.|:.:|......:..|..:|  |.....|.....|    |..|.:.
Mouse   817 QQPHTNQEQYSSPYKSLGNNSSNEKGKATNKWEDSFFSFIKGRSADSDSDCHTL----DKSIASP 877

  Fly   426 GERPGDQNFEIIIDYKNLMRQERDSGLNQLQDEMAPIAFIAESKEMRHLLQHPLISSFLFLKWHR 490
            .|.....:.|.|:..:.:..|:|.|..|....|        ...::..|..||...:..|...:.
Mouse   878 KEGMSHDHHEEIMTGQEVDSQQRLSSENYFSQE--------NDLKVHPLTTHPQEEAVNFCDSNL 934

  Fly   491 LSV 493
            :||
Mouse   935 ISV 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pain	NP_611979.1	ANKYR	2..>182	CDD:440430	36/141 (26%)
		ANK repeat	82..111	CDD:293786	9/30 (30%)
		ANK repeat	113..152	CDD:293786	13/38 (34%)
		ANKYR	<243..>406	CDD:440430	38/217 (18%)
		ANK repeat	324..366	CDD:293786	11/49 (22%)
		ANK repeat	368..393	CDD:293786	5/41 (12%)
		Ion_trans	495..746	CDD:459842
Ankrd31	NP_001357857.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..215
		ANKYR	<469..614	CDD:440430	45/181 (25%)
		ANK repeat	475..506	CDD:293786	9/27 (33%)
		ANK 1. /evidence=ECO:0000255	475..504		8/25 (32%)
		ANK repeat	508..539	CDD:293786	11/39 (28%)
		ANK 2. /evidence=ECO:0000255	508..537		10/37 (27%)
		ANK 3. /evidence=ECO:0000255	541..570		13/65 (20%)
		ANK repeat	541..566	CDD:293786	10/32 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	676..711		5/35 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	813..844		4/30 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	995..1038
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1046..1065
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1075..1137
		ANKYR	<1148..1297	CDD:440430
		ANK 4. /evidence=ECO:0000255	1162..1191
		ANK repeat	1163..1193	CDD:293786
		ANK repeat	1195..1226	CDD:293786
		ANK 5. /evidence=ECO:0000255	1195..1224
		ANK repeat	1228..1259	CDD:293786
		ANK 6. /evidence=ECO:0000255	1228..1257
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1457..1479
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1540..1570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1609..1640
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1663..1697
		RAMA	1683..1785	CDD:465856