DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc2 and LEU5

DIOPT Version :9

Sequence 1:NP_001246511.1 Gene:Tpc2 / 37983 FlyBaseID:FBgn0035078 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_011865.1 Gene:LEU5 / 856391 SGDID:S000001044 Length:357 Species:Saccharomyces cerevisiae


Alignment Length:346 Identity:87/346 - (25%)
Similarity:157/346 - (45%) Gaps:61/346 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 NSVVVQLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYAEEGM 68
            ||....:...:.|||:|:..:|:..|||.:||.||......|.:.||.. |::.|.|.::..:|:
Yeast    28 NSFDYIVRSGLAGGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLI-GLVEAAKHIWINDGV 91

  Fly    69 RGMFRGHNSGQVLSISYALVQFWSYEQLRSM---AHQFD-YWRERPFLMFFICGGIAGCLGAVAA 129
            ||.|:||::..:....||.|:|.:|||:|:.   :.:|: :||.      .:.|.:||.......
Yeast    92 RGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFESHWRR------LVSGSLAGLCSVFIT 150

  Fly   130 QPFDVVRTQMVAADPSSRRSQMNTFTGLRKVYKMEG----------------WMGLSRGLPFTLV 178
            .|.|:||.:: |.:...:|.::...  ::|:||...                |....||...|::
Yeast   151 YPLDLVRVRL-AYETEHKRVKLGRI--IKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVL 212

  Fly   179 QVFPLVGANFLFYKYLN----------AAVLMAKPPD--------QRQEIHGAFLFLNGALSGVL 225
            .:.|..|.:|..:..|:          .:||.....|        ||:.:......::|.|:|:.
Yeast   213 GMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGMA 277

  Fly   226 AKMIVYPADLLKKRIQLMAFKQERKT-----FGRNPECPTILGCITTTFREEGIGGFYKGMLPTL 285
            ::...||.:::::|:|:.|...  ||     |....|...|:      |:|.|:.||:.|:....
Yeast   278 SQTAAYPFEIIRRRLQVSALSP--KTMYDHKFQSISEIAHII------FKERGVRGFFVGLSIGY 334

  Fly   286 LKAGLMSAVYFSIYDMFKRHY 306
            :|...|.|..|.:|:..|.::
Yeast   335 IKVTPMVACSFFVYERMKWNF 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc2NP_001246511.1 PTZ00169 23..304 CDD:240302 80/323 (25%)
Mito_carr 23..99 CDD:278578 28/75 (37%)
Mito_carr 108..194 CDD:278578 19/101 (19%)
Mito_carr 216..307 CDD:278578 25/96 (26%)
LEU5NP_011865.1 Mito_carr 32..127 CDD:395101 32/95 (34%)
PTZ00169 38..329 CDD:240302 78/308 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0752
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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